Evidence map›Paper›PMID 25273357›Full record

ArticleJournal of epidemiology and community health2015

Individual differences in cognitive ability at age 20 predict pulmonary function 35 years later.

Terrie Vasilopoulos, William S Kremen, Michael D Grant, Matthew S Panizzon, Hong Xian, Rosemary Toomey, Michael J Lyons, Kristen C Jacobson, Carol E Franz

Open access · greenAbstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of epidemiology and community health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Intelligence, health and death.Nature human behaviour · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Terrie VasilopoulosDepartment of Anesthesiology, College of Medicine, University of Florida, Gainesville, Florida, USA.
William S KremenDepartment of Psychiatry, University of California, San Diego, La Jolla, California, USA Center for Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, California, USA.
Michael D GrantDepartment of Psychology, Ohio University, Athens, Ohio, USA.
Matthew S PanizzonDepartment of Psychiatry, University of California, San Diego, La Jolla, California, USA.
Hong XianDepartment of Biostatistics, Saint Louis University, St. Louis, Missouri, USA VA St. Louis Healthcare System, St. Louis, Missouri, USA.
Rosemary ToomeyDepartment of Psychology, Boston University, Boston, Massachusetts, USA.
Michael J LyonsDepartment of Psychology, Boston University, Boston, Massachusetts, USA.
Kristen C JacobsonDepartment of Psychiatry & Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA.
Carol E FranzDepartment of Psychiatry, University of California, San Diego, La Jolla, California, USA.
University of California, San Diego · USBoston University · USOhio University · USUniversity of Chicago · USUniversity of Florida · USVA St. Louis Health Care System · US

Funding

The VETSA Longitudinal MRI Twin Study of AgingR01AG022381 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KREMEN, WILLIAM S. · 2003 to 2019
$22.3M
The VETSA Longitudinal Twin Study of Cognition and AgingR01AG018384 · NIA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI LYONS, MICHAEL J. · 2002 to 2012
$9.8M
The VETSA longitudinal twin study of cognition and agingR01AG018386 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KREMEN, WILLIAM S. · 2002 to 2012
$9.7M
The VETSA Longitudinal Twin Study of Cortisol and AgingR01AG022982 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KREMEN, WILLIAM S. · 2004 to 2007
$2.6M
Biopsychosocial approaches to healthy agingF32AG039954 · NIA · UNIVERSITY OF CHICAGO · PI VASILOPOULOS, TERRIE · 2011 to 2012
$105k
NIA NIH HHS F32 AG039954NIA NIH HHS F32AG039954NIA NIH HHS R01 AG018384NIA NIH HHS R01AG018384NIA NIH HHS R01 AG018386NIA NIH HHS R01AG018386NIA NIH HHS R01 AG022381NIA NIH HHS R01AG022381NIA NIH HHS R01 AG022982NIA NIH HHS R01AG022982
6 · The paper itself

Abstract

backgroundPoor pulmonary function is associated with mortality and age-related diseases, and can affect cognitive performance. However, extant longitudinal studies indicate that early cognitive ability also affects later pulmonary function. Despite the multifaceted nature of pulmonary function, most longitudinal studies were limited to a single index of pulmonary function: forced expiratory volume in 1 s (FEV1). In this study, we examined whether early adult cognitive ability predicted five different indices of pulmonary function in mid-life.

methodsMixed modelling tested the association between young adult general cognitive ability (mean age=20), measured by the Armed Forces Qualification Test (AFQT), and mid-life pulmonary function (mean age=55), in 1019 men from the Vietnam Era Twin Study of Aging. Pulmonary function was indexed by per cent predicted values for forced vital capacity (FVC%p), FEV1%p, maximum forced expiratory flow (FEFmax%p), and maximal voluntary ventilation (MVV%p), and by the ratio of FEV1 to FVC (FEV1/FVC), an index of lung obstruction.

resultsAfter adjusting for smoking, pulmonary disease, occupation, income and education, age 20 AFQT was significantly (p<0.05) associated with mid-life FVC%p (β=0.10), FEV1%p (β=0.13), FEFmax%p (β=0.13), and MVV%p (β=0.13), but was not significantly associated with FEV1/FVC (β=0.03, p=0.34).

conclusionsEarly adult cognitive ability is a predictor of multiple indices of aging-related pulmonary function 35 years later, including lung volume, airflow and ventilator capacity. Cognitive deficits associated with impaired aging-related lung function may, thus, be partly pre-existing. However, results also highlight that early life risk factors may be differentially related to different metrics of later-life pulmonary health.

Indexed as

CognitionAdolescentAdultAgingCognition DisordersComorbidityConfounding Factors, EpidemiologicEducational StatusForced Expiratory Flow RatesForced Expiratory VolumeForecastingHumansIndividualityLongitudinal StudiesLungMaleCOGNITIONEPIDEMIOLOGYLONGITUDINAL STUDIESPHYSICAL FUNCTION

Identifiers

PMID25273357
PMCPMC4756634
OpenAlexW2150197640

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.