Evidence map›Paper›PMID 25273204›Full record

ArticleChaos (Woodbury, N.Y.)2014

Continuous-time control of alternans in long Purkinje fibers.

Alejandro Garzón, Roman O Grigoriev, Flavio H Fenton

Abstract read
In one paragraph

Article in Chaos (Woodbury, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Sensitivity of a data-assimilation system for reconstructing three-dimensional cardiac electrical dynamics.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alejandro GarzónSchool of Exact Sciences and Engineering, Universidad Sergio Arboleda, Bogotá, Colombia.
Roman O GrigorievSchool of Physics, Georgia Institute of Technology, Atlanta, Georgia 30332-0430, USA.
Flavio H FentonSchool of Physics, Georgia Institute of Technology, Atlanta, Georgia 30332-0430, USA.

Funding

Dynamical Heterogeneity of Refractoriness and the Induction of ReentryR01HL089271 · NHLBI · ROCHESTER INSTITUTE OF TECHNOLOGY · PI OTANI, NIELS F · 2009 to 2013
$2.2M
NHLBI NIH HHS R01 HL089271NHLBI NIH HHS R01HL089271
6 · The paper itself

Abstract

Alternans-an arrhythmic response of cardiac tissue to periodic pacing-often serves as a precursor to a more dangerous, and potentially lethal, state of fibrillation. Suppression of alternans using feedback control may be a plausible method to prevent fibrillation. Several approaches based on impulsive control have been proposed previously, where feedback is applied for a brief instance of time during each pacing interval. This paper presents a continuous-time approach, where feedback current is applied at all times, which is capable of suppressing alternans in fibers of significantly greater length (up to at least 4 cm), compared with impulsive control (less than 1 cm), and for a wide range of pacing cycle lengths.

Indexed as

Models, CardiovascularModels, NeurologicalAtrial FibrillationCardiac Pacing, ArtificialHumansPurkinje Fibers

Identifiers

PMID25273204
PMCPMC4144161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.