ArticleClinical and translational gastroenterology2014
Colorectal Cancer Incidence Rates in the Louisiana Acadian Parishes Demonstrated to be Among the Highest in the United States.
Article in Clinical and translational gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Industrial Pollution and Health in Louisiana: A Systematic Review of Quantitative and Qualitative Studies.Current environmental health reports · 2026Pooled it
- Building Engagement Using Financial Incentives for Colorectal Cancer Screening (BENEFIT-C) in a Rural Louisiana Federally Qualified Health Center.Health services research · 2026Trial
- Geographic determinants of colorectal cancer in Louisiana.Cancer causes & control : CCC · 2022Article
- Practice patterns and results of tumor and germline genetic evaluation of women with endometrial cancer in south Louisiana.Gynecologic oncology reports · 2021Article
- Geographic and intra-racial disparities in early-onset colorectal cancer in the SEER 18 registries of the United States.Cancer medicine · 2020Article
- Cancer in wildlife: patterns of emergence.Nature reviews. Cancer · 2018Review
- The American College of Gastroenterology and the 80% by 2018 Colorectal Cancer Initiative: A Multifaceted Approach to Maximize Screening Rates.The American journal of gastroenterology · 2017Article
- Diagnosis of Lynch syndrome before colorectal resection: does it matter?Techniques in coloproctology · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDetermine whether colorectal cancer (CRC) rates are disproportionately high in the French-Acadian region (population 1.2 million) of Louisiana, home of the Cajuns, a founder population.
methods2005-2009 cancer incidence rates were stratified by age/race/gender in the 18 Acadian parish region and 9-parish subgroup with higher proportions of French speakers and compared with Louisiana and United States rates. Parishes were identified through language census data. A total of 3,288 CRC cases were identified in the Acadian region and 11,737 in Louisiana.
resultsCRC rates in whites and white males in the 18 parishes were statistically significantly higher than both Louisiana and US rates. In the 9 parishes, rates increased further; whites had an incidence of 56.1/100,000, 13% higher than Louisiana (P<0.0003) and 23% higher than US rates (P<0.0001). In white males, incidence was 72.6/100,000, 19% higher than Louisiana (P<0.0002) and 37% higher than US rates (P<0.0001). If the 9-parish regions were considered a "state," white males would have the highest CRC incidence in the United States by 11% (P<0.0175) compared with other white male populations.
conclusionsCRC rates are among the highest in the United States, increasing with the proportion of French speakers, a marker for the Cajun population. This appears to be the first study identifying a high rate of cancer in a large, regional, US founder population, raising the possibility of a genetic predisposition. Alternatively, an unidentified, robust environmental risk factor may be present. Future studies are needed to identify genetic and/or other risk factors in this population.
Identifiers
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Registered trials
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