Evidence map›Paper›PMID 25273118›Full record

ArticleJournal of neurogastroenterology and motility2014

Validation and diagnostic usefulness of gastroesophageal reflux disease questionnaire in a primary care level in Mexico.

Miguel Angel Zavala-Gonzales, Amyra Ali Azamar-Jacome, Arturo Meixueiro-Daza, Antonio Ramos, Job Reyes-Huerta J, Federico Roesch-Dietlen, Jose Maria Remes-Troche

Registry-linked trialAbstract read
In one paragraph

Article in Journal of neurogastroenterology and motility, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02575287 (Mucosal and Minimal Injuries Detected Through Digital Chromoendoscopy Using Optical Enhancement System™ Associated to High Definition Plus Optical Magnification in Non Erosive Gastroesophageal Reflux Disease), which is not on this map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02575287 completednot on this mapstarted 2015, after this paper: background citation

Mucosal and Minimal Injuries Detected Through Digital Chromoendoscopy Using Optical Enhancement System™ Associated to High Definition Plus Optical Magnification in Non Erosive Gastroesophageal Reflux Disease

TypeobservationalSponsorInstituto Ecuatoriano de Enfermedades DigestivasRan2015 to 2016Enrolled100ConditionsNon Erosive Reflux Disease, GERDArmsOptical Enhancement, Optical Enhancement with optical magnification, Optical magnification without Optical enhancement
3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Trial
  2. A Randomized Placebo-ControlledCanadian journal of gastroenterology & hepatology · 2019
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  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Translation, cultural adaptation, and evaluation of the psychometric properties of the Arabic Gastroesophageal Reflux Disease Questionnaire (Ar-GerdQ).Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miguel Angel Zavala-GonzalesLaboratory of Digestive Physiology and Gastrointestinal Motility, Instituto de Investigaciones Médico - Biológicas, Universidad Veracruzana, Veracruz, México.
Amyra Ali Azamar-JacomeLaboratory of Digestive Physiology and Gastrointestinal Motility, Instituto de Investigaciones Médico - Biológicas, Universidad Veracruzana, Veracruz, México.
Arturo Meixueiro-DazaLaboratory of Digestive Physiology and Gastrointestinal Motility, Instituto de Investigaciones Médico - Biológicas, Universidad Veracruzana, Veracruz, México.
Antonio RamosRegional Hospital of High Specialty of Veracruz,Veracruz, México.
Job Reyes-Huerta JLaboratory of Digestive Physiology and Gastrointestinal Motility, Instituto de Investigaciones Médico - Biológicas, Universidad Veracruzana, Veracruz, México.
Federico Roesch-DietlenLaboratory of Digestive Physiology and Gastrointestinal Motility, Instituto de Investigaciones Médico - Biológicas, Universidad Veracruzana, Veracruz, México.
Jose Maria Remes-TrocheLaboratory of Digestive Physiology and Gastrointestinal Motility, Instituto de Investigaciones Médico - Biológicas, Universidad Veracruzana, Veracruz, México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsDifferent non-invasive diagnostics strategies have been used to assess patients with gastroesophageal reflux. Gastroesophageal reflux disease (GERD) questionnaire (GerdQ) is a 6-item, easy to use questionnaire that was developed primarily as a diagnostic tool for GERD in primary care. Our aim was to validate and assess diagnostic utility of GerdQ questionnaire in Mexican patients in the primary care setting.

methodsThe study was performed in 3 phases: (1) a questionnaire translation and comprehension study (n = 20), (2) are a reproduci-bility and validation study (50 patients and 50 controls) and (3) a study to assess the clinical utility in 252 subjects with GERD symptoms. Diagnostic accuracy was calculated using endoscopy and/or pH-metry as the gold standard.

resultsInternal consistency measured by the Cronbach's α coefficient was 0.81 for patients and 0.90 for healthy controls, with a mixed coefficient of 0.93. Reproducibility for GerdQ was very good and its discriminating validity was 88%. Most of the pa-tients with erosive reflux and non-erosive reflux with abnormal pH-metry had scores > 8, meanwhile most of the patients with functional heartburn and hypersensitive esophagus had < 8. Sensitivity, specificity and positive predictive value of GerdQ com-pared to the gold standard were 72%, 72% and 87%, respectively.

conclusionsIn Mexico, the GerdQ questionnaire Spanish validated version is useful for GERD diagnosis in the primary care setting.(J Neurogastroenterol Motil 2014;20:475-482).

Indexed as

Gastroesophageal refluxMexicoQuestionnairesSensitivity and specificity

Identifiers

PMID25273118
PMCPMC4204416

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.