Observational studyJournal of epidemiology and community health2015
Associations of chronic individual-level and neighbourhood-level stressors with incident coronary heart disease: the Multi-Ethnic Study of Atherosclerosis.
Observational study in Journal of epidemiology and community health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 36 citations in OpenAlex.
- Socioeconomic status as a potential mediator of arterial aging in marginalized ethnic and racial groups: current understandings and future directions.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Review
- Structural and social determinants of health: The multi-ethnic study of atherosclerosis.PloS one · 2024Article
- Racial and Ethnic Residential Segregation and Monocyte DNA Methylation Age Acceleration.JAMA network open · 2023Article
- Associations of emotional social support, depressive symptoms, chronic stress, and anxiety with hard cardiovascular disease events in the United States: the multi-ethnic study of atherosclerosis (MESA).BMC cardiovascular disorders · 2023Article
- Perceived neighborhood factors, health behaviors, and related outcomes in the Hispanic Community Health Study/Study of Latinos.Preventive medicine · 2022Article
- Effect of Social Environments on Cardiovascular Disease in the United States.Journal of the American Heart Association · 2022Article
- Chronic Stress Burden, Visceral Adipose Tissue, and Adiposity-Related Inflammation: The Multi-Ethnic Study of Atherosclerosis.Psychosomatic medicine · 2021Article
- The Interplay between Child Maltreatment and Stressful Life Events during Adulthood and Cardiovascular Problems-A Representative Study.Journal of clinical medicine · 2021Article
- Examining Optimism, Psychosocial Risks, and Cardiovascular Health Using Life's Simple 7 Metrics in the Multi-Ethnic Study of Atherosclerosis and the Jackson Heart Study.Frontiers in cardiovascular medicine · 2021Article
- Associations of regional-level perceived stress and depression with health-related quality of life in Korean adults: a multilevel analysis of 2017 Korea Community Health Survey data.Epidemiology and health · 2021Article
- Neighborhood crime is differentially associated with cardiovascular risk factors as a function of race and sex.Journal of public health research · 2019Article
- Cellular response to chronic psychosocial stress: Ten-year longitudinal changes in telomere length in the Multi-Ethnic Study of Atherosclerosis.Psychoneuroendocrinology · 2019Article
- Stress, Resilience, and Cardiovascular Disease Risk Among Black Women.Circulation. Cardiovascular quality and outcomes · 2019Observational
- Explaining the Relationship Between Minority Group Status and Health Disparities: A Review of Selected Concepts.Health equity · 2019Review
- Unequal Exposure or Unequal Vulnerability? Contributions of Neighborhood Conditions and Cardiovascular Risk Factors to Socioeconomic Inequality in Incident Cardiovascular Disease in the Multi-Ethnic Study of Atherosclerosis.American journal of epidemiology · 2018Article
- Women's heart health at mid-life: what is the role of psychosocial stress?Women's midlife health · 2018Review
- Cardiovascular disease in racial/ethnic minority populations: illness burden and overview of community-based interventions.Public health reviews · 2018Review
- Association of Neighborhood Socioeconomic Context With Participation in Cardiac Rehabilitation.Journal of the American Heart Association · 2017Article
- Number of recent stressful life events and incident cardiovascular disease: Moderation by lifetime depressive disorder.Journal of psychosomatic research · 2017Article
- A novel approach for measuring residential socioeconomic factors associated with cardiovascular and metabolic health.Journal of exposure science & environmental epidemiology · 2017Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundSeveral individual-level stressors have been linked to incident coronary heart disease (CHD), but less attention has focused on the influence of neighbourhood-level sources of stress. In this study we examined prospective associations of individual-level and neighbourhood-level stressors with incident CHD.
methodsMulti-Ethnic Study of Atherosclerosis participants aged 45-84 years at baseline (2000-2002) with complete data were included in the analyses (n=6678 for individual-level and n=6105 for neighbourhood-level stressors). CHD was defined as non-fatal myocardial infarction, resuscitated cardiac arrest or CHD death. Median follow-up was 10.2 years. Multivariable Cox proportional hazards models were fitted to estimate associations of individual-level and neighbourhood-level stressors (categorised into approximate tertiles) with incident CHD.
resultsHigher reported individual-level stressors were associated with higher incident CHD. Participants in the high individual-level stressor category had 65% higher risk of incident CHD (95% CI 1.23 to 2.22) than those in the low category after adjusting for sociodemographics (P for trend=0.002). This association weakened but remained significant with further adjustment for behavioural and biological risk factors. There was a non-linear relationship between neighbourhood-level stressors and incident CHD (P for quadratic term=0.01). Participants in the medium category had 49% higher CHD risk (95% CI 1.06 to 2.10) compared with those in the low category; those in the high category had only 27% higher CHD risk (95% CI 0.83 to 1.95). These associations persisted with adjustment for risk factors and individual-level stressors.
conclusionsIndividual-level and neighbourhood-level stressors were independently associated with incident CHD, though the nature of the relationships differed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.