ArticleJournal of gastroenterology2015
Prospective evaluation of endoscopic criteria characteristic of sessile serrated adenomas/polyps.
Article in Journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Endoscopic diagnosis of sessile serrated polyp: A systematic review.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2019Pooled it
- Usefulness of narrow-band imaging for the detection of remnant sessile-serrated adenoma (SSA) tissue after endoscopic resection: the KASID multicenter study.Surgical endoscopy · 2021Trial
- Article
- 3-D pathological analysis of varicose microvascular vessels in sessile serrated lesions seen on endoscopy.Endoscopy · 2026Article
- Efficacy of image-enhanced endoscopy for colorectal polyp detection.Clinical endoscopy · 2026Review
- Management of Colorectal Sessile Serrated Lesions in Elderly Patients.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Endoscopic Assessment and Management of Colorectal Serrated Lesions: Current Comparative Practice, Challenges, and Future Directions.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Impact of Magnification Endoscopy on Diagnostic Accuracy and Confidence in Real-Time Histological Prediction of Colorectal Lesions: A Prospective Multicenter Study.Journal of gastroenterology and hepatology · 2025Article
- Sessile serrated lesions involving the appendiceal orifice: Endoscopic diagnosis and treatment.World journal of gastrointestinal endoscopy · 2025Review
- Endoscopic characteristics to differentiate SSLs and microvesicular hyperplastic polyps from goblet cell-rich hyperplastic polyps.Endoscopy international open · 2024Article
- Endoscopic characteristics and performance of WASP classification in the diagnosis of colorectal sessile-serrated lesions in Vietnamese patients.JGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Article
- The Comparison of Diagnostic Ability between Blue Laser/Light Imaging and Narrowband Imaging for Sessile Serrated Lesions with or without Dysplasia.Gastroenterology research and practice · 2024Article
- Sessile serrated lesions with dysplasia: is it possible to nip them in the bud?Journal of gastroenterology · 2023Review
- Usefulness of Acetic Acid Spray with Narrow-Band Imaging for Identifying the Margin of Sessile Serrated Lesions.Digestive diseases and sciences · 2023Article
- Current progress on the endoscopic features of colorectal sessile serrated lesions.World journal of clinical oncology · 2023Review
- Clinicopathological features and expression of regulatory mechanism of the Wnt signaling pathway in colorectal sessile serrated adenomas/polyps with different syndrome types.World journal of clinical cases · 2023Article
- Article
- Analysis of Texture and Color Enhancement Imaging for Improving the Visibility of Non-polypoid Colorectal Lesions.Digestive diseases and sciences · 2022Review
- Usefulness of the Japan narrow-band imaging expert team classification system for the diagnosis of sessile serrated lesion with dysplasia/carcinoma.Surgical endoscopy · 2021Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDifferentiating sessile serrated adenoma/polyp (SSA/P) from hyperplastic polyp (HP) is clinically important in determining the necessity of endoscopic resection or recommending appropriate surveillance. There are few reports of characterization of SSA/P using narrowband imaging and chromoendoscopy with and without magnification. We aimed to establish imaging criteria to aid real-time diagnosis of SSA/P.
methodsPatients with pale sessile or flat lesions of 6 mm or greater were prospectively enrolled in this multicenter trial. Nine endoscopic criteria, determined in real time, were investigated for possible association with SSA/P. Endoscopic mucosal resection was performed; specimens were retrieved and analyzed by histopathological examination.
resultsIn 63 patients, 89 lesions were detected, including 41 HP, 38 SSA/P, five mixed polyps, and five other lesions. Right-side colon location, lesion size of 10 mm or greater, excessive mucus, the presence of a varicose microvascular vessel (VMV) noted with high-magnification narrowband imaging, and type III(H) pit pattern were each commonly associated with SSA/P compared with HP. Multivariate analysis substantiated three independent endoscopic criteria for SSA/P: the presence of VMV (p = 0.001), lesion size of 10 mm or greater (p = 0.0017), and right-side location (p = 0.0041), with odds ratios of 8.2, 7.2, and 6.1, respectively. The presence of VMV had a significantly higher specificity (87.8%) than the other two independent endoscopic criteria (p = 0.0007 and p = 0.0008, respectively), but a lower sensitivity (57.9%), whereas a combination of the three criteria (two or more positive) increased the sensitivity significantly (89.5% and p = 0.0033) and had a higher degree of accuracy (82.3%).
conclusionsThree endoscopic criteria individually and in combination were effective in predicting a diagnosis of SSA/P without the need for chromoendoscopy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.