Evidence map›Paper›PMID 25270701›Full record

Trial reportJournal of the American Dental Association (1939)2014

Implications of medical screenings of patients arriving for dental treatment: the results of a comprehensive laboratory screening.

Craig S Miller, Philip M Westgate

Open access · greenAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Dental Association (1939), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Craig S MillerDr. Miller is a professor of oral medicine, Department of Oral Health Practice, Center for Oral Health Research, Oral Medicine Section, MN 324, College of Dentistry, University of Kentucky, 800 Rose St., Lexington, Ky. 40536-0297, e-mail cmiller@uky.edu. Address correspondence to Dr. Miller.
Philip M WestgateDr. Westgate is an assistant professor, Department of Biostatistics, College of Public Health, University of Kentucky, Lexington.
University of Kentucky · US

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
Center for the Biologic Basis of Oral/Systemic Disease (CBBOSD)P20GM103538 · NIGMS · UNIVERSITY OF KENTUCKY · PI EBERSOLE, JEFFREY L · 2012 to 2013
$4.2M
NCATS NIH HHS UL1 TR000117NCATS NIH HHS UL1TR000117NIGMS NIH HHS P20 GM103538
6 · The paper itself

Abstract

backgroundThe authors conducted medical laboratory screenings in a dental setting to determine the relationships between the laboratory test results and self-reported medical health findings.

methodsThe authors collected serum, urine and medical histories from 171 patients (116 [68 percent] women; mean age, 43.4 years) who arrived for dental treatment as a component of a clinical trial and performed complete blood cell counts, standard blood chemistry panels and urinalysis on the samples.

resultsThe authors found 414 abnormal laboratory test results (an average of 2.42 per patient). Eighty-three percent of participants had one or more abnormal test results, 83 percent had abnormal test results and did not indicate a relevant disease in their medical history, and 18 percent had laboratory test results outside the 99 percent reference range (that is, > three standard deviations from the mean). Abnormal test results were significantly associated with sex, age, race and medical history (P< .05). Abnormal test results associated with kidney disease were related to patients with cardiovascular disease and diabetes, as well as those who tended to be on average older than 50 years.

conclusionsThe high frequency of significant abnormal laboratory test results detected in this study suggests that many patients may be unaware of their medical statuses. PRACTICAL IMPLICATIONS: Abnormal laboratory test results are detected frequently in the serum and urine of patients arriving for dental treatment, which could indicate undiagnosed disease and less than optimal medical management.

Indexed as

Clinical Laboratory TechniquesDental ClinicsMass ScreeningAdultAge FactorsAsianBlack or African AmericanBlood Cell CountBlood Chemical AnalysisCardiovascular DiseasesDiabetes MellitusFemaleHerpes LabialisHumansKidney DiseasesMalePlacebosbloodclinical laboratory techniqueslaboratory screeningMass screeningmedical history takingserumurine

Identifiers

PMID25270701
PMCPMC4388436
OpenAlexW65109133

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.