ArticleDysphagia2015
The effect of bilateral superior laryngeal nerve lesion on swallowing: a novel method to quantitate aspirated volume and pharyngeal threshold in videofluoroscopy.
Article in Dysphagia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 33 citations in OpenAlex.
- A ducted, biomimetic nipple replicates breastfeeding mechanics through ontogeny in an infant animal model.Pediatric research · 2026Article
- Marmoset (Callithrix jacchus) Swallowing Physiology: Novel Dysphagia Model Across Lifespan.Integrative and comparative biology · 2026Article
- Research advances in dysphagia animal models.Animal models and experimental medicine · 2025Review
- Age-Related Changes in Marmoset (Callithrix jacchus) Feeding Behavior and Physiology: Insights of Masticatory and Swallowing Functions.American journal of primatology · 2025Article
- The effects of simulated gastroesophageal reflux on infant pig oropharyngeal feeding physiology.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Oropharyngeal swallowing hydrodynamics of thin and mildly thick liquids in an anatomically accurate throat-epiglottis model.Scientific reports · 2024Article
- Exploring the interaction of viscosity and nipple design on feeding performance in an infant pig model.Journal of texture studies · 2023Article
- Oropharyngeal capsaicin exposure improves infant feeding performance in an animal model of superior laryngeal nerve damage.Journal of neurophysiology · 2022Article
- Laryngeal and swallow dysregulation following acute cervical spinal cord injury.Journal of neurophysiology · 2022Article
- Increased viscosity of milk during infant feeding improves swallow safety through modifying sucking in an animal model.Journal of texture studies · 2021Article
- Swallow Safety is Determined by Bolus Volume During Infant Feeding in an Animal Model.Dysphagia · 2021Article
- Measuring Vallecular Volume on Flexible Endoscopic Evaluation of Swallowing: A Proof of Concept Study.Dysphagia · 2021Article
- Pathophysiology of aspiration in a unilateral SLN lesion model using quantitative analysis of VFSS.International journal of pediatric otorhinolaryngology · 2021Article
- Adaptations to Oral and Pharyngeal Swallowing Function Induced by Injury to the Mylohyoid Muscle.Dysphagia · 2020Article
- Article
- Premature birth impacts bolus size and shape through nursing in infant pigs.Pediatric research · 2020Article
- Preterm Birth Impacts the Timing and Excursion of Oropharyngeal Structures during Infant Feeding.Integrative organismal biology (Oxford, England) · 2020Article
- Specific Vagus Nerve Lesion Have Distinctive Physiologic Mechanisms of Dysphagia.Frontiers in neurology · 2019Article
- Maturation of the Coordination Between Respiration and Deglutition with and Without Recurrent Laryngeal Nerve Lesion in an Animal Model.Dysphagia · 2018Article
- Impact of recurrent laryngeal nerve lesion on oropharyngeal muscle activity and sensorimotor integration in an infant pig model.Journal of applied physiology (Bethesda, Md. : 1985) · 2018Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
The purpose was to determine the effect of bilateral superior laryngeal nerve (SLN) lesion on swallowing threshold volume and the occurrence of aspiration, using a novel measurement technique for videofluoroscopic swallowing studies (VFSS) in infant pigs. We used a novel radiographic phantom to assess volume of the milk containing barium from fluoroscopy. The custom made phantom was firstly calibrated by comparing image intensity of the phantom with known cylinder depths. Secondly, known volume pouches of milk in a pig cadaver were compared to volumes calculated with the phantom. Using these standards, we calculated the volume of milk in the valleculae, esophagus and larynx, for 205 feeding sequences from four infant pigs feeding before and after had bilateral SLN lesions. Swallow safety was assessed using the tested and validated IMPAS (Dysphagia 28(2):178-187, 2013). The log-linear correlation between image intensity values from the phantom filled with barium milk and the known phantom cylinder depths was strong (R (2) > 0.95), as was the calculated volumes of the barium milk pouches. The threshold volume of bolus in the valleculae during feeding was significantly larger after bilateral SLN lesion than in control swallows (p < 0.001). The IMPAS score increased in the lesioned swallows relative to the controls, indicating substantially impaired swallowing (p < 0.001). Bilateral SLN lesion dramatically increased the aspiration incidence and the threshold volume of bolus in valleculae. The use of this phantom permits quantification of the aspirated volume of fluid, allowing for more accurate 3D volume estimation from 2D X-ray in VFSS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.