Evidence map›Paper›PMID 25268886›Full record

ArticleAIDS (London, England)2015

Persistent HIV-related stigma in rural Uganda during a period of increasing HIV incidence despite treatment expansion.

Brian T Chan, Sheri D Weiser, Yap Boum, Mark J Siedner, A Rain Mocello, Jessica E Haberer, Peter W Hunt, Jeffrey N Martin, Kenneth H Mayer, David R Bangsberg and 1 more

Abstract read
In one paragraph

Article in AIDS (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

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  10. "African geographical review · 2024
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  19. HIV-AIDS Stigma in Burundi: A Qualitative Descriptive Study.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 3 countries.

Brian T ChanaDivision of Infectious Diseases, Massachusetts General Hospital bDivision of Infectious Diseases, Brigham and Women's Hospital cHarvard Medical School, Boston, Massachusetts dDivision of HIV/AIDS, San Francisco General Hospital, University of California at San Francisco (UCSF) eCenter for AIDS Prevention Studies, UCSF, San Francisco, California, USA fEpicentre, Mbarara, Uganda gMassachusetts General Hospital Center for Global Health, Boston, Massachusetts hDepartment of Epidemiology and Biostatistics, UCSF, San Francisco, California iDivision of Infectious Diseases, Beth Israel Deaconess Medical Center jFenway Health, Boston, Massachusetts, USA kMbarara University of Science and Technology, Mbarara, Uganda lChester M. Pierce, MD Division of Global Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Sheri D Weiser
Yap Boum
Mark J Siedner
A Rain Mocello
Jessica E Haberer
Peter W Hunt
Jeffrey N Martin
Kenneth H Mayer
David R Bangsberg
Alexander C Tsai
Division of Chemistry · USUniversity of California, San Francisco · USApple (Israel) · ILBrigham and Women's Hospital · USCenter for Global Health · USEpicentre Uganda · UGHadassah Medical Center · ILHarvard University · USMbarara University of Science and Technology · UG

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
TB PREVENTION AND HIV IN THE HOMELESS--AN INTERVENTIONR01MH054907 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BANGSBERG, DAVID ROY · 1995 to 2014
$20.7M
West Coast AIDS and Cancer Specimen Resource (ACSR)U01CA066529 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCGRATH, MICHAEL SHANNON · 1994 to 2012
$16.1M
PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
Microenterprise to empower and improve health of HIV+ women in UgandaK23MH096620 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI TSAI, ALEXANDER C · 2012 to 2016
$922k
The Impact of Food Insecurity on HIV Outcomes and Sexual Risk Behavior in UgandaK23MH079713 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEISER, SHERI DAWN · 2007 to 2011
$921k
Behavioral Aspects of Low-cost Medical Devices to Improve HIV CareK23MH099916 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI SIEDNER, MARK J · 2013 to 2017
$917k
Novel Measures and Theory of Pediatric Antiretroviral Therapy Adherence in UgandaK23MH087228 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI HABERER, JESSICA ELIZABETH · 2009 to 2013
$916k
Mentoring Patient Oriented Adherence Research in UgandaK24MH087227 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BANGSBERG, DAVID ROY · 2009 to 2013
$776k
NCI NIH HHS U01 CA066529NCI NIH HHS U01CA066529NIAID NIH HHS P30 AI027763NIAID NIH HHS P30 AI060354NIAID NIH HHS P30AI060354NIAID NIH HHS P30AI27763NIAID NIH HHS T32 AI007433NIAID NIH HHS T32AI007433NIMH NIH HHS K23 MH079713NIMH NIH HHS K23MH079713NIMH NIH HHS K23 MH087228NIMH NIH HHS K23MH087228NIMH NIH HHS K23 MH096620NIMH NIH HHS K23MH096620NIMH NIH HHS K23 MH099916NIMH NIH HHS K23MH099916NIMH NIH HHS K24 MH087227NIMH NIH HHS K24MH087227NIMH NIH HHS P30 MH062246NIMH NIH HHS R01 MH054907NIMH NIH HHS R01MH054907
6 · The paper itself

Abstract

objectiveProgramme implementers have argued that the increasing availability of antiretroviral therapy (ART) will reduce the stigma of HIV. We analyzed data from Uganda to assess how HIV-related stigma has changed during a period of ART expansion.

designSerial cross-sectional surveys.

methodsWe analyzed data from the Uganda AIDS Rural Treatment Outcomes study during 2007-2012 to estimate trends in internalized stigma among people living with HIV (PLHIV) at the time of treatment initiation. We analyzed data from the Uganda Demographic and Health Surveys from 2006 to 2011 to estimate trends in stigmatizing attitudes and anticipated stigma in the general population. We fitted regression models adjusted for sociodemographic characteristics, with year of data collection as the primary explanatory variable.

resultsWe estimated an upward trend in internalized stigma among PLHIV presenting for treatment initiation [adjusted b = 0.18; 95% confidence interval (CI), 0.06-0.30]. In the general population, the odds of reporting anticipated stigma were greater in 2011 compared with 2006 [adjusted odds ratio (OR) = 1.80; 95% CI, 1.51-2.13], despite an apparent decline in stigmatizing attitudes (adjusted OR = 0.62; 95% CI, 0.52-0.74).

conclusionInternalized stigma has increased over time among PLHIV in the setting of worsening anticipated stigma in the general population. Further study is needed to better understand the reasons for increasing HIV-related stigma in Uganda and its impact on HIV prevention efforts.

Indexed as

Social StigmaAdultCross-Sectional StudiesData CollectionFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansIncidenceMaleOdds RatioRural PopulationTreatment OutcomeUganda

Identifiers

PMID25268886
PMCPMC4286463
OpenAlexW2091146032

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.