ArticleThe Analyst2014
Online SERS detection of the 20 proteinogenic L-amino acids separated by capillary zone electrophoresis.
Article in The Analyst, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 68 citations in OpenAlex.
- Digital surface enhanced Raman spectroscopy for quantifiable single molecule detection in flow.The Analyst · 2024Article
- Raman and Surface-Enhanced Raman Scattering Detection in Flowing Solutions for Complex Mixture Analysis.Annual review of analytical chemistry (Palo Alto, Calif.) · 2024Review
- From the lab to the field: handheld surface enhanced Raman spectroscopy (SERS) detection of viral proteins.Sensors & diagnostics · 2023Article
- Raman Scattering Study of Amino Acids Adsorbed on a Silver Nanoisland Film.Sensors (Basel, Switzerland) · 2022Article
- Determination of lentiviral titer by surface enhanced Raman scattering.Analytical methods : advancing methods and applications · 2022Article
- 3-D printed injection system for capillary electrophoresis.Analytical methods : advancing methods and applications · 2022Article
- Ultra-sensitive and fast optical detection of the spike protein of the SARS-CoV-2 using AgNPs/SiNWs nanohybrid based sensors.Surfaces and interfaces · 2021Article
- Catching COVID: Engineering Peptide-Modified Surface-Enhanced Raman Spectroscopy Sensors for SARS-CoV-2.ACS sensors · 2021Article
- Micro- and Nanoscale Spectroscopic Investigations of Threonine Influence on the Corrosion Process of the Modified Fe Surface by Cu Nanoparticles.Materials (Basel, Switzerland) · 2020Article
- Microchip isotachophoresis coupled to surface-enhanced Raman spectroscopy for pharmaceutical analysis.Mikrochimica acta · 2020Article
- Article
- Untargeted Tumor Metabolomics with Liquid Chromatography-Surface-Enhanced Raman Spectroscopy.Angewandte Chemie (International ed. in English) · 2020Article
- Bioanalytical applications of surface-enhanced Raman spectroscopy:Reviews in analytical chemistry · 2017Article
- Sheath flow SERS for chemical profiling in urine.Faraday discussions · 2016Article
- Increased SERS detection efficiency for characterizing rare events in flow.Analytical chemistry · 2015Article
- Micellar electrokinetic chromatography method for measuring amino acid secretions from islets of Langerhans.Electrophoresis · 2015Article
- Sheath-flow microfluidic approach for combined surface enhanced Raman scattering and electrochemical detection.Analytical chemistry · 2015Article
- Online SERS detection and characterization of eight biologically-active peptides separated by capillary zone electrophoresis.The Analyst · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A sheath-flow surface-enhanced Raman scattering (SERS) detector is demonstrated to provide chemical information enabling identification of the 20 proteinogenic L-amino acids separated by capillary zone electrophoresis (CZE). Amino acids were used to illustrate the chemical specificity of SERS detection from structurally related molecules. Analysis of the SERS electropherograms obtained from the separation and sequential online detection of six groups of structurally related amino acids shows that our sheath-flow SERS detector is able to resolve the characteristic Raman bands attributed to the amine, carboxyl, and side chain constituents. The results demonstrate the chemical information available from our detector and also provide insight into the nature of the analyte interaction with the silver SERS substrate. The spectra extracted from the SERS electropherogram of a mixture containing the 20 proteinogenic L-amino acids show unique signatures characteristic to each amino acid, thus enabling identification. The results presented here demonstrate the potential of this sheath-flow SERS detector as a general purpose method for high throughput characterization and identification following separations of complex biomolecular mixtures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.