Evidence map›Paper›PMID 25268383›Full record

ArticlePloS one2014

Genome-wide association study for wool production traits in a Chinese Merino sheep population.

Zhipeng Wang, Hui Zhang, Hua Yang, Shouzhi Wang, Enguang Rong, Wenyu Pei, Hui Li, Ning Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 153 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Genomic insights into the recent evolution and biodiversity of Italian sheep breeds.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  5. Article
  6. Genetic Polymorphism RevealsAnimals : an open access journal from MDPI · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Genome-Wide Association Study of Fiber Diameter in Alpacas.Animals : an open access journal from MDPI · 2023
    Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhipeng WangKey Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang province, Harbin, P. R. China; College of Animal Science and Technology, Northeast Agricultural University, Harbin, P. R. China.
Hui ZhangKey Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang province, Harbin, P. R. China; College of Animal Science and Technology, Northeast Agricultural University, Harbin, P. R. China.
Hua YangInstitute of Animal Husbandry and Veterinary, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, P.R. China.
Shouzhi WangKey Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang province, Harbin, P. R. China; College of Animal Science and Technology, Northeast Agricultural University, Harbin, P. R. China.
Enguang RongKey Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang province, Harbin, P. R. China; College of Animal Science and Technology, Northeast Agricultural University, Harbin, P. R. China.
Wenyu PeiKey Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang province, Harbin, P. R. China; College of Animal Science and Technology, Northeast Agricultural University, Harbin, P. R. China.
Hui LiKey Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang province, Harbin, P. R. China; College of Animal Science and Technology, Northeast Agricultural University, Harbin, P. R. China.
Ning WangKey Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang province, Harbin, P. R. China; College of Animal Science and Technology, Northeast Agricultural University, Harbin, P. R. China.
Education Department of Heilongjiang Province · CNNortheast Agricultural University · CNXinjiang Academy of Agricultural and Reclamation Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide association studies (GWAS) provide a powerful approach for identifying quantitative trait loci without prior knowledge of location or function. To identify loci associated with wool production traits, we performed a genome-wide association study on a total of 765 Chinese Merino sheep (JunKen type) genotyped with 50 K single nucleotide polymorphisms (SNPs). In the present study, five wool production traits were examined: fiber diameter, fiber diameter coefficient of variation, fineness dispersion, staple length and crimp. We detected 28 genome-wide significant SNPs for fiber diameter, fiber diameter coefficient of variation, fineness dispersion, and crimp trait in the Chinese Merino sheep. About 43% of the significant SNP markers were located within known or predicted genes, including YWHAZ, KRTCAP3, TSPEAR, PIK3R4, KIF16B, PTPN3, GPRC5A, DDX47, TCF9, TPTE2, EPHA5 and NBEA genes. Our results not only confirm the results of previous reports, but also provide a suite of novel SNP markers and candidate genes associated with wool traits. Our findings will be useful for exploring the genetic control of wool traits in sheep.

Indexed as

AnimalsGenome-Wide Association StudyPolymorphism, Single NucleotideSheep, DomesticWool

Identifiers

PMID25268383
PMCPMC4182092
OpenAlexW2025758091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.