Evidence map›Paper›PMID 25267937›Full record

ArticleSchizophrenia research. Cognition2014

A novel, online social cognitive training program for young adults with schizophrenia: A pilot study.

Mor Nahum, Melissa Fisher, Rachel Loewy, Gina Poelke, Joseph Ventura, Keith H Nuechterlein, Christine I Hooker, Michael F Green, Mike Merzenich, Sophia Vinogradov

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Schizophrenia research. Cognition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03962426 (Elucidating the Efficacy and Response to Social Cognitive Training), which is not on this map. Cited by 57 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 6 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03962426 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Elucidating the Efficacy and Response to Social Cognitive Training (SCT) in Recent Onset Psychosis (ROP)

TypeinterventionalSponsorLudwig-Maximilians - University of MunichRan2016 to 2020Enrolled66ConditionsPsychosisArmsSocialVille Social Cognitive Training
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 6 syntheses or guidelines pooled it, 108 citations in OpenAlex.

  1. Pooled it
  2. Mend the Gap: Online User-Led Adjuvant Treatment for Psychosis: A Systematic Review on Recent Findings.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Mor NahumPosit Science, 77 Geary St., Suite 303, San Francisco, CA 94108 ; Department of Optometry, University of California, Berkeley, 487 Minor Hall, Berkeley, CA 94720.
Melissa FisherDepartment of Psychiatry, University of California, San Francisco ; San Francisco Department of Veterans Affairs Medical Center, 4150 Clement St., San Francisco, CA 94121.
Rachel LoewySan Francisco Department of Veterans Affairs Medical Center, 4150 Clement St., San Francisco, CA 94121.
Gina PoelkeDepartment of Psychiatry, University of California, San Francisco ; San Francisco Department of Veterans Affairs Medical Center, 4150 Clement St., San Francisco, CA 94121.
Joseph VenturaDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 300 UCLA Medical Plaza, LA, CA 90095.
Keith H NuechterleinDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 300 UCLA Medical Plaza, LA, CA 90095 ; Department of Psychology, University of California, Los Angeles.
Christine I HookerDepartment of Psychology, Harvard University, William James Hall 1020, 33 Kirkland St., Cambridge, MA 02138.
Michael F GreenDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 300 UCLA Medical Plaza, LA, CA 90095 ; VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd., LA CA 90073 ( mgreen@ucla.edu ).
Mike MerzenichPosit Science, 77 Geary St., Suite 303, San Francisco, CA 94108.
Sophia VinogradovDepartment of Psychiatry, University of California, San Francisco ; San Francisco Department of Veterans Affairs Medical Center, 4150 Clement St., San Francisco, CA 94121.
University of California, San Francisco · USUniversity of California, Los Angeles · USHarvard University · USPosit Science (United States) · USUniversity of California, Berkeley · US

Funding

Computerized Plasticity-Based Training to Remediate Deficits in Social CognitionR43MH091793 · NIMH · BRAIN PLASTICITY, INC. · PI NAHUM, MOR · 2011 to 2012
$498k
NIMH NIH HHS R43 MH091793
6 · The paper itself

Abstract

backgroundPervasive social cognition deficits are evident early in the course of schizophrenia and are directly linked to functional outcome, making them an important target for intervention. Here, we tested the feasibility of use, and initiated the evaluation of efficacy, of a novel, neuroplasticity-based online training program (SocialVille) in young adults with schizophrenia.

methodsSchizophrenia patients (n=17) completed 24 hours of online SocialVille game play either from home or at a clinic, over a 6-10 week period. We examined training feasibility, gains on the SocialVille exercises relative to matched healthy controls (n=17), and changes on measures of social cognition, social functioning, global functioning and motivation.

resultsSubjects adhered to training requirements, and rated SocialVille in the medium to high range in satisfaction, enjoyment, and ease of use. Subjects demonstrated significant, large improvements on the speeded SocialVille tasks, and small to moderate improvements on the working memory tasks. Post-training performance on the SocialVille tasks were similar to initial performance of the healthy controls. Subjects also showed improvements on standard measures of social cognition, social functioning, and motivation. No improvements were recorded for emotion recognition indices on the MSCEIT, or on quality of life scales.

conclusionThis study provides an initial proof of concept for online social cognition training in schizophrenia. This form of training demonstrated feasibility and resulted in within-subject gains in social functioning and motivation. This pilot study represents a first step towards validating this training approach; randomized controlled trials, now underway, are designed to confirm and extend these findings.

Indexed as

cognitive remediationcomputerized trainingearly psychosisfirst episodesocial cognition

Identifiers

PMID25267937
PMCPMC4175473
OpenAlexW2126475148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.