Evidence map›Paper›PMID 25267933›Full record

ArticleJournal of glycomics & lipidomics2011

Clustered Conserved Cysteines in Hyaluronan Synthase Mediate Cooperative Activation by Mg

Valarie L Tlapak-Simmons, Andria P Medina, Bruce A Baggenstoss, Long Nguyen, Christina A Baron, Paul H Weigel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of glycomics & lipidomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Valarie L Tlapak-SimmonsDepartment of Biochemistry & Molecular Biology, The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.
Andria P MedinaDepartment of Biochemistry & Molecular Biology, The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.
Bruce A BaggenstossDepartment of Biochemistry & Molecular Biology, The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.
Long NguyenDepartment of Biochemistry & Molecular Biology, The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.
Christina A BaronDepartment of Biochemistry & Molecular Biology, The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.
Paul H WeigelDepartment of Biochemistry & Molecular Biology, The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.

Funding

STRUCTURE/FUNCTION OF HYALURANAN BINDING PROTEINS/RECEPTR01GM035978 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI WEIGEL, PAUL H · 1986 to 2012
$4.1M
NIGMS NIH HHS R01 GM035978
6 · The paper itself

Abstract

Hyaluronan synthase (HAS) uses UDP-GlcUA and UDP-GlcNAc to make hyaluronan (HA).

Indexed as

CooperativityCysteine clusterEnzyme kineticsMutagenesisStreptococcal

Identifiers

PMID25267933
PMCPMC4176928

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.