Evidence map›Paper›PMID 25267903›Full record

ArticleThe Cochrane database of systematic reviews2012

Fixed-dose combination therapy for the prevention of cardiovascular disease.

Angharad N de Cates, Matthew Rb Farr, Karen Rees, Juan P Casas, Mark Huffman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Angharad N de CatesDivision of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.
Matthew Rb FarrDivision of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.
Karen ReesDivision of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.
Juan P CasasDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine; Department of Epidemiology and Public Health, University College London, London, UK.
Mark HuffmanDepartments of Preventative Medicine and Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows: To determine the effectiveness of fixed-dose combination therapy on optimising CVD risk factors and reducing CVD fatal and non-fatal events for both primary and secondary prevention of CVD. Details of CVD events and risk factors included are listed in the methods. We will also determine any adverse events associated with taking fixed-dose combination therapy. This will include studies conducted in both developed and developing regions of the world.

Identifiers

PMID25267903
PMCPMC4176631

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.