Trial reportImplementation science : IS2014
Protocol: Adaptive Implementation of Effective Programs Trial (ADEPT): cluster randomized SMART trial comparing a standard versus enhanced implementation strategy to improve outcomes of a mood disorders program.
Trial report in Implementation science : IS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02151331 (Improving Mental Health Outcomes), which is not on this map. Cited by 83 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Mental Health Outcomes: Building an Adaptive Implementation
Who cites it
83 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Statistical design and analysis in trials of proportionate interventions: a systematic review.Trials · 2019Pooled it
- Student mental health outcomes of a clustered SMART for developing an adaptive implementation strategy to support school-based CBT delivery.Journal of affective disorders · 2024Trial
- Organize and mobilize for implementation effectiveness to improve overdose education and naloxone distribution from syringe services programs: a randomized controlled trial.Implementation science : IS · 2024Trial
- Baseline data of a sequential multiple assignment randomized trial (STEP study).Early intervention in psychiatry · 2022Trial
- Primary aim results of a clustered SMART for developing a school-level, adaptive implementation strategy to support CBT delivery at high schools in Michigan.Implementation science : IS · 2022Trial
- Translating Violence Prevention Programs from Research to Practice: SafERteens Implementation in an Urban Emergency Department.The Journal of emergency medicine · 2022Trial
- Optimal allocation to treatments in a sequential multiple assignment randomized trial.Statistical methods in medical research · 2021Trial
- Implementation of peer specialist services in VA primary care: a cluster randomized trial on the impact of external facilitation.Implementation science : IS · 2021Trial
- Comparative effectiveness of external vs blended facilitation on collaborative care model implementation in slow-implementer community practices.Health services research · 2020Trial
- Trial
- Adaptive School-based Implementation of CBT (ASIC): clustered-SMART for building an optimized adaptive implementation intervention to improve uptake of mental health interventions in schools.Implementation science : IS · 2018Trial
- Choosing Among Randomized Design Families for Implementation Strategy Trials: A Question-Driven Framework with Practical Tools and Exemplars.Research square · 2026Article
- A review of use of external data and update on reporting standards in Sequential Multiple-Assignment Randomised Trials.Clinical trials (London, England) · 2026Review
- Achieving cardiovascular health equity in community mental health: study protocol for a cluster-randomized hybrid Type 3 effectiveness-implementation trial.Implementation science : IS · 2025Article
- Understanding inequitable health care: methodological approaches, challenges, and opportunities.American journal of epidemiology · 2025Article
- Integrating implementation science and intervention optimization.Implementation science : IS · 2025Article
- Adapting Public Health and Health Services Interventions in Diverse, Real-World Settings: Documentation and Iterative Guidance of Adaptations.Annual review of public health · 2025Review
- Standard vs. enhanced implementation strategies to increase adoption of a multidrug-resistant organism alert tool: a cluster randomized trial.Frontiers in health services · 2025Article
- Can theory-driven implementation interventions help clinician champions promote opioid stewardship after childbirth? Protocol for a pragmatic implementation study.Frontiers in global women's health · 2025Article
- Reducing asthma attacks in disadvantaged school children with asthma: study protocol for a type 2 hybrid implementation-effectiveness trial (Better Asthma Control for Kids, BACK).Implementation science : IS · 2024Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
backgroundDespite the availability of psychosocial evidence-based practices (EBPs), treatment and outcomes for persons with mental disorders remain suboptimal. Replicating Effective Programs (REP), an effective implementation strategy, still resulted in less than half of sites using an EBP. The primary aim of this cluster randomized trial is to determine, among sites not initially responding to REP, the effect of adaptive implementation strategies that begin with an External Facilitator (EF) or with an External Facilitator plus an Internal Facilitator (IF) on improved EBP use and patient outcomes in 12 months. METHODS/
designThis study employs a sequential multiple assignment randomized trial (SMART) design to build an adaptive implementation strategy. The EBP to be implemented is life goals (LG) for patients with mood disorders across 80 community-based outpatient clinics (N = 1,600 patients) from different U.S. regions. Sites not initially responding to REP (defined as < 50% patients receiving ≥ 3 EBP sessions) will be randomized to receive additional support from an EF or both EF/IF. Additionally, sites randomized to EF and still not responsive will be randomized to continue with EF alone or to receive EF/IF. The EF provides technical expertise in adapting LG in routine practice, whereas the on-site IF has direct reporting relationships to site leadership to support LG use in routine practice. The primary outcome is mental health-related quality of life; secondary outcomes include receipt of LG sessions, mood symptoms, implementation costs, and organizational change. DISCUSSION: This study design will determine whether an off-site EF alone versus the addition of an on-site IF improves EBP uptake and patient outcomes among sites that do not respond initially to REP. It will also examine the value of delaying the provision of EF/IF for sites that continue to not respond despite EF.
trial registrationClinicalTrials.gov identifier: NCT02151331.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.