Evidence map›Paper›PMID 25267050›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2014

Prevalence and costs of treating uncomplicated stage 1 hypertension in primary care: a cross-sectional analysis.

James P Sheppard, Kate Fletcher, Richard J McManus, Jonathan Mant

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Role of the Pharmacoeconomic Aspects in the Clinical Management of Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

James P SheppardNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Kate FletcherPrimary Care Clinical Sciences, University of Birmingham, Birmingham.
Richard J McManusNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Jonathan MantPrimary Care Unit, University of Cambridge, Cambridge.
University of Oxford · GBUniversity of Birmingham · GB

Funding

Department of Health CDF/01/017Department of Health NIHR-RP-02-12-015Department of Health PB-PG-1207-15042Department of Health RP-PG-0606-1153Department of Health RP-PG-1209-10051Medical Research Council MR/K022032/1
6 · The paper itself

Abstract

backgroundTreatment for uncomplicated stage 1 hypertension is recommended in most international guidelines but there is little evidence to indicate that therapy is beneficial.

aimTo estimate the prevalence of this condition in an untreated population and the potential costs of initiating therapy in such patients. DESIGN AND

settingCross-sectional study of anonymised patient records in 19 general practices in the West Midlands, UK.

methodData relating to patient demographics, existing cardiovascular disease (CVD), and risk factors (blood pressure and cholesterol) were extracted from patient records. Patients with a blood pressure of 140/90-159/99 mmHg, no CVD, and <20% 10-year cardiovascular risk were classified as having uncomplicated stage 1 hypertension. Missing data were imputed. The prevalence of untreated, uncomplicated stage 1 hypertension was estimated using descriptive statistics and extrapolated using national data. The cost of achieving blood pressure control in this population was examined in a cost-impact analysis using published costs from previous studies.

resultsOf the 34 975 patients (aged 40-74 years) in this study, untreated, uncomplicated stage 1 hypertension was present in 2867 individuals (8.2%, 95% confidence interval [CI] = 7.9 to 8.5). This is equivalent to 1 892 519 patients in England and Wales, for whom the additional cost of controlling blood pressure, according to guidelines, was estimated at £106-229 million per annum, depending on the health professional delivering care.

conclusionUntreated, uncomplicated stage 1 hypertension is relatively common, affecting 1 in 12 patients aged 40-74 years in primary care. Current international guidelines and pay-for-performance targets, if followed, will incur significant costs for a patient benefit that is debatable.

Indexed as

Primary Health CareAdultAgedAntihypertensive AgentsCardiovascular DiseasesCost-Benefit AnalysisCross-Sectional StudiesEnglandFemaleGeneral PracticeHumansHypertensionMaleMiddle AgedPractice Guidelines as TopicPrevalenceAntihypertensive Agentsantihypertensive agentscardiovascular disease riskguidelinesprimary prevention

Identifiers

PMID25267050
PMCPMC4173727
OpenAlexW2131521202

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.