Evidence map›Paper›PMID 25266989›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2014

Bio-efficacy of the essential oil of oregano (Origanum vulgare Lamiaceae. Ssp. Hirtum).

Ezequiel Grondona, Gerardo Gatti, Abel G López, Leonardo Rodolfo Sánchez, Virginia Rivero, Oscar Pessah, María P Zunino, Andrés A Ponce

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 35 citations in OpenAlex.

  1. TheMethods and protocols · 2025
    Review
  2. Gels (Basel, Switzerland) · 2025
    Article
  3. Hydroxypropyl Cellulose Hydrogel ContainingGels (Basel, Switzerland) · 2024
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  4. Review
  5. Review
  6. An Up-To-Date Review Regarding Cutaneous Benefits ofAntibiotics (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Article
  9. A Review of the Phytochemistry and Antimicrobial Properties ofIranian journal of pharmaceutical research : IJPR · 2021
    Review
  10. Article
  11. Oregano (International journal of nutrition · 2019
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ezequiel GrondonaCátedra de Fisiología Humana, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Gerardo Gatti
Abel G López
Leonardo Rodolfo Sánchez
Virginia Rivero
Oscar Pessah
María P Zunino
Andrés A Ponce
Universidad Nacional de Córdoba · ARInstituto Multidisciplinario de Biología Vegetal · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the bioactivity of the essential oil isolated from Origanum vulgare L. (EOv). We analyzed the in vivo anti-inflammatory properties in a mouse-airway inflammation model and the in vitro antimicrobial activity, genotoxicity over the anaphase-telophase with the Allium cepa strain and its cytotoxicity/viability in A549 culture cells. In vivo, EOv modified the levels of tumor necrosis factor -α and viable activated macrophages and was capable to mitigate the effects of degradation of conjugated dienes. In vitro, EOv reduced the viability of cultured A549 cells as well as the mitotic index and a number of chromosomal aberrations; however, it did not change the number of phases. We found that EOv presents antimicrobial activity against different Gram (-) and (+) strains, measured by disc-diffusion test and confirmed with a more accurate method, the AutoCad software. We postulate that EOv presents antibacterial, antioxidant and chemopreventive properties and could be play an important role as bioprotector agent.

Indexed as

PhytotherapyAdenocarcinomaAdenocarcinoma of LungAlliumAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsBacteriaCell Line, TumorHumansLung NeoplasmsMacrophagesMaleMiceAnti-Bacterial AgentsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsOils, VolatilePlant ExtractsPlant OilsTumor Necrosis Factor-alpha

Identifiers

PMID25266989
OpenAlexW1996036157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.