Evidence map›Paper›PMID 25266230›Full record

SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2015

Meniscal allograft transplantation. Part 2: systematic review of transplant timing, outcomes, return to competition, associated procedures, and prevention of osteoarthritis.

Gonzalo Samitier, Eduard Alentorn-Geli, Dean C Taylor, Brian Rill, Terrence Lock, Vasilius Moutzouros, Patricia Kolowich

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Low-impact sports activities are feasible after meniscus transplantation: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018
    Pooled it
  2. Is meniscal allograft transplantation chondroprotective? A systematic review of radiological outcomes.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2016
    Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Treatment, Return to Play, and Performance Following Meniscus Surgery.Current reviews in musculoskeletal medicine · 2022
    Review
  15. Article
  16. Autologous semitendinosus tendon graft could function as a meniscal transplant.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Article
  17. Human meniscus allograft augmentation by allogeneic mesenchymal stromal/stem cell injections.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  18. Article
  19. Article
  20. [Arthroscopic meniscus transplantation without bone blocks].Operative Orthopadie und Traumatologie · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gonzalo SamitierDepartment of Orthopaedics, Sports Medicine Division, Henry Ford Health System, William Clay Ford Center for Athletic Medicine, 6525 Second Avenue, Detroit, MI, 48202, USA.
Eduard Alentorn-Geli
Dean C Taylor
Brian Rill
Terrence Lock
Vasilius Moutzouros
Patricia Kolowich
Henry Ford Health System · USDuke Medical Center · USDuke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide a systematic review of the literature regarding five topics in meniscal allograft transplantation (MAT): optimal timing for transplantation, outcomes, return to competition, associated procedures, and prevention of osteoarthritis.

methodsA systematic literature search was conducted using the PubMed (MEDLINE), ScienceDirect, and EBSCO-CINAHL databases. Articles were classified only in one topic, but information contained could be reported into other topics. Information was classified according to type of study (animal, in vitro human, and in vivo human) and level of evidence (for in vivo human studies). Specific inclusion criteria were determined for the outcomes and prevention of osteoarthritis topics.

resultsTwenty-four studies were finally included: two optimal timing, seven outcomes, three return to competitive sport, 16 MAT and associated procedures, and 5 MAT and prevention of osteoarthritis (some studies were categorized in more than one topic). These studies corresponded to 2 animal studies and 31 in vivo human studies (1 level II, 1 level III, and 29 level IV).

conclusionsThe principal conclusions were as follows: (a) there is no evidence to support that MAT has to be performed at the same time or immediately after meniscectomy to prevent development of postmeniscectomy syndrome; (b) MAT successfully improves symptoms, function, and quality of life at 7-to-14 years of follow-up (level IV evidence); (c) the overall failure rate (need for knee arthroplasty) is 10-29% at long-term follow-up; (d) MAT allows return to same level of competition in 75-85% of patients at short- to mid-term follow-up (only three studies level IV evidence with small sample size); (e) associated cartilage procedures or anterior cruciate ligament reconstruction to MAT does not worsen the results; (f) MAT may prevent progression of cartilage damaged at long-term follow-up, but may not prevent degeneration in previously healthy cartilage. LEVEL OF EVIDENCE: Systematic review of level II-IV studies, Level IV.

Indexed as

AllograftsAnimalsArthroplastyHumansKnee InjuriesKnee JointMenisci, TibialOsteoarthritis, KneeTibial Meniscus InjuriesTime FactorsTransplantation, HomologousTreatment Outcome

Identifiers

PMID25266230
OpenAlexW2031063460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.