ReviewNature reviews. Nephrology2014
An approach to cystic kidney diseases: the clinician's view.
Review in Nature reviews. Nephrology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- A rare case of advanced CKD with extensive cystic renal disease causing bowel obstruction.Annals of medicine and surgery (2012) · 2025Article
- Impact of Chronic Kidney Disease on Aortic Dissection in Patients with Polycystic Kidney Disease: A Fifteen-year Nationwide Population-based Cohort Study in Taiwan.International journal of medical sciences · 2025Article
- Genetic and radiological aspects of pediatric renal cystic disease: A case seriesBiomedica : revista del Instituto Nacional de Salud · 2024Article
- Single-Center Experience of Pediatric Cystic Kidney Disease and Literature Review.Children (Basel, Switzerland) · 2024Article
- TheBiomedicines · 2024Review
- Editorial: Cystic kidney diseases in children and adults: from diagnosis to etiology and back.Frontiers in pediatrics · 2024Article
- Clinical and biochemical footprints of inherited metabolic diseases. XIV. Metabolic kidney diseases.Molecular genetics and metabolism · 2023Article
- Hypertrophic and fibrotic human PKD hearts are associated with macrophage infiltration and abnormal TGF-βCell and tissue research · 2023Article
- Massive Acquired Renal Cysts Presenting with Bowel Obstruction-Like Symptoms.Case reports in medicine · 2022Article
- Management of autosomal-dominant polycystic kidney disease-state-of-the-art.Clinical kidney journal · 2018Review
- Comprehensive genetic testing in children with a clinical diagnosis of ARPKD identifies phenocopies.Pediatric nephrology (Berlin, Germany) · 2018Article
- Young-Adult Polycystic Kidney Disease is Associated with Major Cardiovascular Complications.International journal of environmental research and public health · 2018Article
- Cystic Kidney Diseases From the Adult Nephrologist's Point of View.Frontiers in pediatrics · 2018Review
- Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.Kidney international · 2016Article
- Radiologic imaging of the renal parenchyma structure and function.Nature reviews. Nephrology · 2016Review
- Polycystic kidney disease. HALTing PKD progression--revival of blood pressure control.Nature reviews. Nephrology · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in molecular genetics have led to the identification of more than 70 different genes involved in the development of cystic kidney diseases. Most of these diseases are rare, and interpreting the resultant plethora of disease-causing mutations requires a methodical and meticulous approach to differential diagnosis. In this Review we discuss a clinical approach to the diagnosis of cystic kidney diseases in adults, for use by nephrologists. This approach is based upon a thorough clinical evaluation, which considers both kidney phenotype and extrarenal manifestations of the underlying disorder, in combination with genetic testing in selected patients. In our view, cystic kidney disease can (in the majority of patients) be reliably classified on the basis of clinical findings. We therefore propose that defining clinical situations to precipitate the initiation of genetic testing is mandatory and cost-effective. New techniques such as next-generation sequencing will facilitate the diagnosis of cystic kidney diseases in the future, increasing diagnostic safety in a subset of patients. In renal tumour syndromes, genetic testing is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.