Evidence map›Paper›PMID 25265629›Full record

ArticleIEEE transactions on medical imaging2015

Exact confidence intervals for channelized Hotelling observer performance in image quality studies.

Adam Wunderlich, Frederic Noo, Brandon D Gallas, Marta E Heilbrun

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  6. Virtual clinical trials in medical imaging: a review.Journal of medical imaging (Bellingham, Wash.) · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adam Wunderlich
Frederic Noo
Brandon D Gallas
Marta E Heilbrun

Funding

Ultra-fast whole-heart CT using z-motion of the X-ray sourceR01EB007236 · NIBIB · UNIVERSITY OF UTAH · PI NOO, FREDERIC · 2008 to 2011
$1.3M
Efficient snap-shot CT imaging of the entire heart using staggered circular scansR21EB009168 · NIBIB · UNIVERSITY OF UTAH · PI NOO, FREDERIC · 2009 to 2010
$407k
Intramural FDA HHS FD999999NIBIB NIH HHS R01 EB007236NIBIB NIH HHS R21 EB009168
6 · The paper itself

Abstract

Task-based assessments of image quality constitute a rigorous, principled approach to the evaluation of imaging system performance. To conduct such assessments, it has been recognized that mathematical model observers are very useful, particularly for purposes of imaging system development and optimization. One type of model observer that has been widely applied in the medical imaging community is the channelized Hotelling observer (CHO), which is well-suited to known-location discrimination tasks. In the present work, we address the need for reliable confidence interval estimators of CHO performance. Specifically, we show that the bias associated with point estimates of CHO performance can be overcome by using confidence intervals proposed by Reiser for the Mahalanobis distance. In addition, we find that these intervals are well-defined with theoretically-exact coverage probabilities, which is a new result not proved by Reiser. The confidence intervals are tested with Monte Carlo simulation and demonstrated with two examples comparing X-ray CT reconstruction strategies. Moreover, commonly-used training/testing approaches are discussed and compared to the exact confidence intervals. MATLAB software implementing the estimators described in this work is publicly available at http://code.google.com/p/iqmodelo/.

Indexed as

AlgorithmsDiscriminant AnalysisComputer SimulationHumansImage Processing, Computer-AssistedModels, BiologicalMonte Carlo MethodPhantoms, ImagingSignal-To-Noise RatioTomography, X-Ray ComputedTorso

Identifiers

PMID25265629
PMCPMC5542023

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.