SynthesisPloS one2014
Patients with chronically diseased livers have lower incidence of colorectal liver metastases: a meta-analysis.
Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Metabolic dysfunction-associated steatotic liver disease and immune checkpoint inhibitor response in gastrointestinal liver metastases: current evidence and future directions.Frontiers in nutrition · 2026Review
- An evaluation model of hepatic steatosis based on CT value and serum uric acid/HDL cholesterol ratio can predict intrahepatic recurrence of colorectal cancer liver metastasis.International journal of clinical oncology · 2024Article
- Focal Liver Lesions other than Hepatocellular Carcinoma in Cirrhosis: Diagnostic Challenges.Journal of translational internal medicine · 2022Article
- HBV Infection Status Indicates Different Risks of Synchronous and Metachronous Liver Metastasis in Colorectal Cancer: A Retrospective Study of 3132 Patients with a 5-Year Follow-Up.Cancer management and research · 2022Article
- Higher titer hepatitis B core antibody predicts a higher risk of liver metastases and worse survival in patients with colorectal cancer.World journal of surgical oncology · 2021Article
- Review
- Metastases can occur in cirrhotic livers with patent portal veins.Diagnostic pathology · 2021Article
- Fatty change of the liver microenvironment influences the metastatic potential of colorectal cancer.International journal of experimental pathology · 2020Article
- IEO model: A novel concept describing the complete metastatic process in the liver microenvironment.Oncology letters · 2020Review
- Effect of Non-alcoholic Fatty Liver Disease on the Risk of Synchronous Liver Metastasis: Analysis of 451 Consecutive Patients of Newly Diagnosed Colorectal Cancer.Frontiers in oncology · 2020Article
- Incidence and prognosis of liver metastasis at diagnosis: a pan-cancer population-based study.American journal of cancer research · 2020Article
- Prophylactical Low Dose Whole-Liver Irradiation Inhibited Colorectal Liver Metastasis by Regulating Hepatic Niche in Mice.OncoTargets and therapy · 2020Article
- Non-alcoholic fatty liver disease and colorectal cancer survival.Cancer causes & control : CCC · 2019Article
- Evaluation of Peritumoral Fibrosis in Metastatic Colorectal Adenocarcinoma to the Liver Using Digital Image Analysis.American journal of clinical pathology · 2019Article
- Impact of Hepatitis B Carrier Status on the Outcomes of Surgical Treatment of Colorectal Liver Metastases.World journal of surgery · 2018Article
- Liver surgery in cirrhosis and portal hypertension.World journal of gastroenterology · 2016Review
- IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment.EMBO molecular medicine · 2016Article
- Prediagnostic Plasma Adiponectin and Survival among Patients with Colorectal Cancer.Cancer prevention research (Philadelphia, Pa.) · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background70 years ago, it was put forward that the diseased liver was not a favorable soil for metastatic tumor cells. In addition, a few studies have demonstrated that rare occurrence of colorectal liver metastases among patients with fatty liver, cirrhosis or chronic hepatitis B and C virus infection. We performed a meta-analysis to verify the association between the incidences of colorectal liver metastases with chronically diseased livers.
methodsRelevant studies were identified by a search of electronic database PubMed, Cochrane Library, OVID, Web of Science and CNKI (up to February 24, 2014). Pooled odds ratio (OR) with 95% confidence interval (CI) was calculated using random- or fixed-effect models when appropriate. Meta-analysis and publication bias (Bgger's test) was evaluated with STATA 12.0.
resultsA total of 10,349 colorectal cancer patients from 10 studies were included. The meta-analysis result showed there was a significant difference in the incidences of colorectal liver metastases between patients with normal and chronically diseased livers (OR = 0.32; 95% CI 95%: 0.26-0.38, P = 0.000 fixed-effects model). The result of Begg's test (Pr>|z| = 0.089; P>0.05) revealed no publication bias.
conclusionsThe results of this meta-analysis demonstrated that patients with chronically diseased livers had significantly lower incidences of colorectal liver metastases than those with normal livers.
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