ArticlePloS one2014
The association of meningococcal disease with influenza in the United States, 1989-2009.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 51 citations in OpenAlex.
- Modeling the Impact of Climate Extremes on Seasonal Influenza Outbreaks Across Tropical and Temperate Locations.GeoHealth · 2025Article
- Inference of transmission dynamics and retrospective forecast of invasive meningococcal disease.PLoS computational biology · 2023Article
- Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study.The Lancet regional health. Europe · 2023Article
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- Specialized pro-resolving lipid mediators regulate inflammatory macrophages: A paradigm shift from antibiotics to immunotherapy for mitigating COVID-19 pandemic.Frontiers in molecular biosciences · 2023Review
- Immunogenicity and safety of MenACWY-TT, a quadrivalent meningococcal tetanus toxoid conjugate vaccine recently licensed in the United States for individuals ≥2 years of age.Human vaccines & immunotherapeutics · 2022Article
- Impact of COVID-19 Containment Strategies and Meningococcal Conjugate ACWY Vaccination on Meningococcal Carriage in Adolescents.The Pediatric infectious disease journal · 2022Article
- Bacterial Co-Infection in Patients with COVID-19 Hospitalized (ICU and Not ICU): Review and Meta-Analysis.Antibiotics (Basel, Switzerland) · 2022Review
- The decline of invasive meningococcal disease and influenza in the time of COVID-19: the silver linings of the pandemic playbook.The Medical journal of Australia · 2022Article
- Neisseria meningitidis bacteraemia and SARS-CoV-2 infection: a coinfection that reminds previous epidemic outbreaks.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022Article
- Excess Invasive Meningococcal Disease Associated With Seasonal Influenza, South Africa, 2003-2018.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Bacterial coinfection in influenza pneumonia: Rates, pathogens, and outcomes.Infection control and hospital epidemiology · 2022Article
- Article
- The Host-Pathogen Interactions and Epicellular Lifestyle ofFrontiers in cellular and infection microbiology · 2022Review
- Relationship between influenza and dengue outbreaks, and subsequent bacterial sepsis in French Guiana: A time series analysis.Journal of public health research · 2021Article
- Tracking and predicting U.S. influenza activity with a real-time surveillance network.PLoS computational biology · 2020Article
- Bacterial co-infections with SARS-CoV-2.IUBMB life · 2020Review
- Meningococcal meningitis and COVID-19 co-infection.BMJ case reports · 2020Article
- Association of Influenza Activity and Environmental Conditions With the Risk of Invasive Pneumococcal Disease.JAMA network open · 2020Article
- Epidemiology of invasive meningococcal disease in Cyprus 2004 to 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
IMPORTANCE AND
objectivePrior influenza infection is a risk factor for invasive meningococcal disease. Quantifying the fraction of meningococcal disease attributable to influenza could improve understanding of viral-bacterial interaction and indicate additional health benefits to influenza immunization. DESIGN, SETTING AND
participantsA time series analysis of the association of influenza and meningococcal disease using hospitalizations in 9 states from 1989-2009 included in the State Inpatient Databases from the Agency for Healthcare Research and Quality and the proportion of positive influenza tests by subtype reported to the Centers for Disease Control. The model accounts for the autocorrelation of meningococcal disease and influenza between weeks, temporal trends, co-circulating respiratory syncytial virus, and seasonality. The influenza-subtype-attributable fraction was estimated using the model coefficients. We analyzed the synchrony of seasonal peaks in hospitalizations for influenza, respiratory syncytial virus, and meningococcal disease. RESULTS AND
conclusionsIn 19 of 20 seasons, influenza peaked≤2 weeks before meningococcal disease, and peaks were highly correlated in time (ρ = 0.95; P <.001). H3N2 and H1N1 peaks were highly synchronized with meningococcal disease while pandemic H1N1, B, and respiratory syncytial virus were not. Over 20 years, 12.8% (95% CI, 9.1-15.0) of meningococcal disease can be attributable to influenza in the preceding weeks with H3N2 accounting for 5.2% (95% CI, 3.0-6.5), H1N1 4.3% (95% CI, 2.6-5.6), B 3.0% (95% CI, 0.8-4.9) and pH1N1 0.2% (95% CI, 0-0.4). During the height of influenza season, weekly attributable fractions reach 59%. While vaccination against meningococcal disease is the most important prevention strategy, influenza vaccination could provide further protection, particularly in young children where the meningococcal disease vaccine is not recommended or protective against the most common serogroup.
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