ArticleCanadian journal of surgery. Journal canadien de chirurgie2014
Factors affecting transfusion requirement after hip fracture: can we reduce the need for blood?
Article in Canadian journal of surgery. Journal canadien de chirurgie, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Preoperative Tranexamic Acid on Blood Loss and Transfusion Rates in Intertrochanteric and Subtrochanteric Femur Fractures.
Efficacy of Intraoperative Periarticular Injections in Reducing Blood Loss and Transfusion Requirements in Hip Fracture Hemiarthroplasty: A Randomized Controlled Trial
Who cites it
30 citing papers in PubMed, 54 citations in OpenAlex.
- A randomised controlled trial assessing the effect of tranexamic acid on post-operative blood transfusions in patient with intra-capsular hip fractures treated with hemi- or total hip arthroplasty.Archives of orthopaedic and trauma surgery · 2024Trial
- Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study.Canadian journal of surgery. Journal canadien de chirurgie · 2021Trial
- Blood Transfusion Risk Following Early Versus Delayed Surgery in Hip Fracture Patients on Direct Oral Anticoagulants: A Study Protocol for a Natural Experiment.Journal of clinical medicine · 2026Article
- Factors Affecting Transfusion Rate for Patients After Hip Fracture.Orthopedic reviews · 2026Article
- Allogeneic blood transfusion after hip fracture: risk factors and associated outcomes.Bulletin of the Hospital for Joint Disease (2013) · 2025Article
- Tranexamic Acid Use in Neck of Femur Fractures: Impact on Blood Loss and Clinical Outcomes at a UK Teaching Hospital.Cureus · 2025Article
- Hemoglobin trends and transfusion risk in isolated femoral shaft fractures: a multi-year retrospective analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Comparison of Hemiarthroplasty, total hip arthroplasty, and internal fixation for hip fractures in patients over eighty years of age: factors affecting mortality: a nationwide cohort study of fifty three thousand, four hundred and ninety five patients from Türkiye.International orthopaedics · 2025Article
- Association between selective serotonin reuptake inhibitors use and blood transfusion risk in older adults after hip fracture: a cohort study.BMC geriatrics · 2024Observational
- An explainable and supervised machine learning model for prediction of red blood cell transfusion in patients during hip fracture surgery.BMC anesthesiology · 2024Article
- Development and validation of machine learning models to predict perioperative transfusion risk for hip fractures in the elderly.Annals of medicine · 2024Article
- Early surgery within 48 h was associated with reduced perioperative blood loss and red blood cell transfusion requirements in older patients with hip fracture: a retrospective study.European geriatric medicine · 2023Article
- Blood-Transfusion Risk Factors after Intramedullary Nailing for Extracapsular Femoral Neck Fracture in Elderly Patients.Journal of functional morphology and kinesiology · 2023Article
- Postoperative haemoglobin estimation in elderly hip fractures.Aging medicine (Milton (N.S.W)) · 2021Article
- Safety and efficacy of a strategy of vitamin K antagonist reversal with prothrombin complex concentrates compared to vitamin K in patients with hip fracture.Canadian journal of surgery. Journal canadien de chirurgie · 2021Article
- Reducing unnecessary crossmatching for hip fracture patients by accounting for preoperative hemoglobin concentration.World journal of orthopedics · 2021Article
- Partial warfarin reversal prior to hip fracture surgical intervention in geriatric trauma patients effects on blood loss and transfusions.Journal of clinical orthopaedics and trauma · 2021Article
- Development of a Nomogram to Predict Postoperative Transfusion in the Elderly After Intramedullary Nail Fixation of Femoral Intertrochanteric Fractures.Clinical interventions in aging · 2021Article
- Red Blood Cell Transfusion and Postoperative Delirium in Hip Fracture Surgery Patients: A Retrospective Observational Cohort Study.Anesthesiology research and practice · 2021Article
- The Correlation Between Timing of Surgery and the Need for RBC Transfusions in the Geriatric Intertrochanteric Fracture Population.Geriatric orthopaedic surgery & rehabilitation · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHip fractures are common injuries that result in blood loss and frequently require the transfusion of blood products. We sought to identify risk factors leading to increased blood transfusion in patients presenting with hip fractures, especially those factors that are modifiable.
methodsWe retrospectively reviewed the cases of all patients who had fixation of their hip fractures between October 2005 and February 2010. The need for transfusion was correlated with potential risk factors, including age, sex, preoperative hemoglobin, fracture type, fixation method and more.
resultsA total of 835 patients had fixation of their hip fractures during the study period; 631 met the inclusion criteria and 249 of them (39.5%) were transfused. We found an association between need for blood transfusion and female sex (p = 0.018), lower preoperative hemoglobin (p < 0.001), fracture type (p < 0.001) and fixation method (p < 0.001). Compared with femoral neck fractures, there was a 2.37 times greater risk of blood transfusion in patients with intertrochanteric fractures (p < 0.001) and a 4.03 times greater risk in those with subtrochanteric fractures (p < 0.001). Dynamic hip screw (DHS) fixation decreased the risk of transfusion by about half compared with intramedullary nail or hemiarthroplasty. We found no association with age, delay to operation (p = 0.17) or duration of surgery (p = 0.30).
conclusionThe only modifiable risk factor identified was fixation method. When considering blood transfusion requirements in isolation, we suggest a potential benefit in using a DHS for intertrochanteric and femoral neck fractures amenable to DHS fixation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.