Evidence map›Paper›PMID 25264826›Full record

ArticlePloS one2014

Lactobacillus rossiae, a vitamin B12 producer, represents a metabolically versatile species within the Genus Lactobacillus.

Maria De Angelis, Francesca Bottacini, Bruno Fosso, Philip Kelleher, Maria Calasso, Raffaella Di Cagno, Marco Ventura, Ernesto Picardi, Douwe van Sinderen, Marco Gobbetti

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Veterinary sciences · 2026
    Article
  3. Proposal ofInternational journal of systematic and evolutionary microbiology · 2025
    Article
  4. Article
  5. International journal of systematic and evolutionary microbiology · 2025
    Article
  6. Review
  7. Article
  8. Postbiotics as Metabolites and Their Biotherapeutic Potential.International journal of molecular sciences · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. Comparative genomics ofComputational and structural biotechnology journal · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Comparative Genomics ofFrontiers in microbiology · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Maria De AngelisDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Bari, Italy.
Francesca BottaciniDepartment of Microbiology, University College Cork, Cork, Ireland.
Bruno FossoDepartment of Bioscience, Biotechnology and Biopharmaceutical, University of Bari Aldo Moro, Bari, Italy.
Philip KelleherDepartment of Microbiology, University College Cork, Cork, Ireland.
Maria CalassoDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Bari, Italy.
Raffaella Di CagnoDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Bari, Italy.
Marco VenturaLaboratory of Probiogenomics, Department of Life Sciences, University of Parma, Parma, Italy.
Ernesto PicardiDepartment of Bioscience, Biotechnology and Biopharmaceutical, University of Bari Aldo Moro, Bari, Italy; Institute of Biomembranes and Bioenergetics (IBBE), CNR, Bari, Italy; National Institute of Biostructures and Biosystems (INBB), Rome, Italy.
Douwe van SinderenDepartment of Microbiology, University College Cork, Cork, Ireland; Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland.
Marco GobbettiDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Bari, Italy.
University of Bari Aldo Moro · ITUniversity College Cork · IEIstituto Nazionale Biostrutture e Biosistemi · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactobacillus rossiae is an obligately hetero-fermentative lactic acid bacterium, which can be isolated from a broad range of environments including sourdoughs, vegetables, fermented meat and flour, as well as the gastrointestinal tract of both humans and animals. In order to unravel distinctive genomic features of this particular species and investigate the phylogenetic positioning within the genus Lactobacillus, comparative genomics and phylogenomic approaches, followed by functional analyses were performed on L. rossiae DSM 15814T, showing how this type strain not only occupies an independent phylogenetic branch, but also possesses genomic features underscoring its biotechnological potential. This strain in fact represents one of a small number of bacteria known to encode a complete de novo biosynthetic pathway of vitamin B12 (in addition to other B vitamins such as folate and riboflavin). In addition, it possesses the capacity to utilize an extensive set of carbon sources, a characteristic that may contribute to environmental adaptation, perhaps enabling the strain's ability to populate different niches.

Indexed as

FermentationGenes, BacterialLactobacillusPhylogenyVitamin B 12Vitamin B 12

Identifiers

PMID25264826
PMCPMC4180280
OpenAlexW2041721363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.