ArticleCurrent biology : CB2014
A temporal channel for information in sparse sensory coding.
Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Hybrid spatial organization and evidence for magnitude-independent neural coding of linguistic information during sentence production.Science advances · 2026Article
- Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells.The Journal of physiology · 2025Article
- The gamma rhythm as a guardian of brain health.eLife · 2024Review
- Human olfactory perception embeds fine temporal resolution within a single sniff.Nature human behaviour · 2024Article
- What do the mushroom bodies do for the insect brain? Twenty-five years of progress.Learning & memory (Cold Spring Harbor, N.Y.) · 2024Article
- Combinatorial encoding of odors in the mosquito antennal lobe.Nature communications · 2023Article
- Olfactory receptor neurons generate multiple response motifs, increasing coding space dimensionality.eLife · 2023Article
- Disorder and the Neural Representation of Complex Odors.Frontiers in computational neuroscience · 2022Article
- Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation.Cell reports · 2021Article
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- Multiple network properties overcome random connectivity to enable stereotypic sensory responses.Nature communications · 2020Article
- Article
- Optimality of sparse olfactory representations is not affected by network plasticity.PLoS computational biology · 2020Article
- Evolutionarily conserved anatomical and physiological properties of olfactory pathway through fourth-order neurons in a species of grasshopper (Hieroglyphus banian).Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019Article
- Separate But Interactive Parallel Olfactory Processing Streams Governed by Different Types of GABAergic Feedback Neurons in the Mushroom Body of a Basal Insect.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Front-end Weber-Fechner gain control enhances the fidelity of combinatorial odor coding.eLife · 2019Article
- Functional architecture of reward learning in mushroom body extrinsic neurons of larval Drosophila.Nature communications · 2018Article
- Calcium in Kenyon Cell Somata as a Substrate for an Olfactory Sensory Memory inFrontiers in cellular neuroscience · 2018Article
- Article
- Plasticity-driven individualization of olfactory coding in mushroom body output neurons.Nature · 2015Article
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Abstract
backgroundSparse codes are found in nearly every sensory system, but the role of spike timing in sparse sensory coding is unclear. Here, we use the olfactory system of awake locusts to test whether the timing of spikes in Kenyon cells, a population of neurons that responds sparsely to odors, carries sensory information to and influences the responses of follower neurons.
resultsWe characterized two major classes of direct followers of Kenyon cells. With paired intracellular and field potential recordings made during odor presentations, we found that these followers contain information about odor identity in the temporal patterns of their spikes rather than in the spike rate, the spike phase, or the identities of the responsive neurons. Subtly manipulating the relative timing of Kenyon cell spikes with temporally and spatially structured microstimulation reliably altered the response patterns of the followers.
conclusionsOur results show that even remarkably sparse spiking responses can provide information through stimulus-specific variations in timing on the order of tens to hundreds of milliseconds and that these variations can determine the responses of downstream neurons. These results establish the importance of spike timing in a sparse sensory code.
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