Evidence map›Paper›PMID 25263801›Full record

ArticleScientific reports2014

High order intra-strand partial symmetry increases with organismal complexity in animal evolution.

Shengqin Wang, Jing Tu, Zhongwei Jia, Zuhong Lu

Abstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shengqin WangState Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Jing TuState Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Zhongwei JiaNational Institute of Drug Dependence, Peking University, Beijing 100191, China.
Zuhong Lu1] State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China [2] Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, 100781, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For sufficiently long genomic sequence, the frequency of any short nucleotide fragment on one strand is approximately equal to the frequency of its reverse complement on the same strand. Despite being studied over two decades, the precise mechanism involved has not yet been made clear. In this study, we calculated the high order intra-strand partial symmetry (IPS) for 14 animal species by using a fixed sliding window method to scan each genome sequence. The study showed that the IPS was positive associated with organismal complexity measured by the number of distinct cell types. The results indicated that the IPS might be resulted from the increasing of functional non-coding DNAs, and plays an important role in the evolution process of complex body plans.

Indexed as

Biological EvolutionEvolution, MolecularGenomeAnimalsBase CompositionBase SequenceHumansSequence Analysis, DNA

Identifiers

PMID25263801
PMCPMC4178289

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.