Evidence map›Paper›PMID 25262591›Full record

ArticleAtencion primaria2015

[A pilot study in a community pharmacy to determine the efficiency and the effectiveness of statin prescriptions].

Jose Miguel Ruiz Maldonado, Blanca Lumbreras, Hortensia Muñoz Jimenez, Jose Manuel Navarrete Carranza, Ignacio Anza Aguirrezabala, Maria Pastor-Valero

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Atencion primaria, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jose Miguel Ruiz MaldonadoFarmacia 334, Lorca, Murcia, España. Electronic address: jmmaldonados@gmail.com.
Blanca LumbrerasDepartamento de Salud Pública, Historia de la Ciencia y Ginecología, Universidad Miguel Hernandez, San Juan de Alicante, CIBERESP (CIBER en Epidemiología y Salud Pública), Alicante, España.
Hortensia Muñoz JimenezFundación para la Formación e Investigación Sanitarias de la Región de Murcia, Murcia, España.
Jose Manuel Navarrete CarranzaFarmacia 334, Lorca, Murcia, España.
Ignacio Anza AguirrezabalaUnidad Docente de Medicina Familiar y Comunitaria de Lorca, Lorca, Murcia, España.
Maria Pastor-ValeroDepartamento de Salud Pública, Historia de la Ciencia y Ginecología, Universidad Miguel Hernandez, San Juan de Alicante, CIBERESP (CIBER en Epidemiología y Salud Pública), Alicante, España.
Fundación para la Formación e Investigación Sanitarias de la Región de Murcia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe efficacy of statins to reduce LDL-cholesterol serum levels is high, but effectiveness is limited and costs are elevated.

objectiveThe efficiency and effectiveness of prescriptions were analyzed in a pilot study in a community pharmacy.

designA cross-sectional study. LOCATION: Community pharmacy. Prescriptions from two Murcian Health Service Centers in Lorca, Murcia (Spain).

participantsA total of 141 patients and 32 general practitioners were included. The efficiency was analyzed in 141 and effectiveness in 110 patients. MAIN MEASUREMENTS: Socio-demographic characteristics and clinical history of patients and information about statin type and dosage were collected. Each patient was analyzed to determine the effectiveness of treatment according to cardiovascular risk and previous LDL-cholesterol level, and efficiency comparing the statin prescribed against other statins with equal pharmacological power.

resultsThe most prescribed statin was atorvastatin (57.4%). Almost two-thirds (63.9%) of prescriptions were inefficient, and 17.3% were ineffective. In a bivariate analysis, patients with previous cardiovascular events (8/38; 21% vs 41/103; 39.8%. P=.040) and smokers (42/114; 36.8% vs 4/23; 17.4%, P=.047) were more likely to receive an inefficient prescription than patients with no cardiovascular events and non-smokers. In a multivariate analysis, smokers were more likely to receive an inefficient prescription than non-smokers (OR ajusted 3.76; 95% CI;1.03-0.77, P=.012).

conclusionsMost of the participants reached therapeutic objectives for LDL-Cholesterol levels, but more than half of the prescriptions were considered inefficient.

Indexed as

Cholesterol, LDLCross-Sectional StudiesFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypercholesterolemiaMaleMiddle AgedPharmaciesPilot ProjectsSpainTreatment OutcomeCholesterol, LDLHydroxymethylglutaryl-CoA Reductase InhibitorsAtención primaria de saludEfectividadEffectivenessEfficiencyEficienciaEstatinasPrimary Health CareStatins

Identifiers

PMID25262591
PMCPMC6985637
OpenAlexW2116010497

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.