Evidence map›Paper›PMID 25262271›Full record

Trial reportAmerican heart journal2014

Physical activity and resting pulse rate in older adults: findings from a randomized controlled trial.

Bríain O'Hartaigh, Marco Pahor, Thomas W Buford, John A Dodson, Daniel E Forman, Thomas M Gill, LIFE Study Group

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in American heart journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Bríain O'HartaighDalio Institute of Cardiovascular Imaging, Weill Cornell Medical College, New York, NY; Department of Internal Medicine/Section of Geriatrics, Yale School of Medicine, New Haven, CT. Electronic address: briain.ohartaigh@yale.edu.
Marco PahorDepartment of Aging and Geriatric Research, University of Florida College of Medicine, Gainesville, FL.
Thomas W BufordDepartment of Aging and Geriatric Research, University of Florida College of Medicine, Gainesville, FL.
John A DodsonLeon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, NY.
Daniel E FormanDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA.
Thomas M GillDepartment of Internal Medicine/Section of Geriatrics, Yale School of Medicine, New Haven, CT.
LIFE Study Group
University of Florida · USYale University · USBrigham and Women's Hospital · USNew York University · US

Funding

UF FIELD CENTERU01AG022376 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PAHOR, MARCO · 2003 to 2015
$83.3M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
UF CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR029890 · NCRR · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2009 to 2011
$14.4M
ACADEMIC LEADERSHIP AWARD IN DISABILITY AND DISABLING DISORDERSK07AG043587 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2013 to 2017
$645k
Intramural NIH HHSNCRR NIH HHS UL1 RR029890NIA NIH HHS K07 AG043587NIA NIH HHS K07AG043587NIA NIH HHS P30 AG021342NIA NIH HHS P30AG021342NIA NIH HHS P30 AG028740NIA NIH HHS U01 AG022376NIA NIH HHS U01 AG22376
6 · The paper itself

Abstract

backgroundElevated resting pulse rate (RPR) is a well-recognized risk factor for adverse outcomes. Epidemiological evidence supports the beneficial effects of regular exercise for lowering RPR, but studies are mainly confined to persons younger than 65 years. We set out to evaluate the utility of a physical activity (PA) intervention for slowing RPR among older adults.

methodsA total of 424 seniors (ages 70-89 years) were randomized to a moderate intensity PA intervention or an education-based "successful aging" health program. Resting pulse rate was assessed at baseline, 6 months, and 12 months. Longitudinal differences in RPR were evaluated between treatment groups using generalized estimating equation models, reporting unstandardized β coefficients with robust SEs.

resultsIncreased frequency and duration of aerobic training were observed for the PA group at 6 and 12 months as compared with the successful aging group (P < .001). In both groups, RPR remained unchanged over the course of the 12-month study period (P = .67). No significant improvement was observed (β [SE] = 0.58 [0.88]; P = .51) for RPR when treatment groups were compared using the generalized estimating equation method. Comparable results were found after omitting participants with a pacemaker, cardiac arrhythmia, or who were receiving β-blockers.

conclusionsTwelve months of moderate intensity aerobic training did not improve RPR among older adults. Additional studies are needed to determine whether PA of longer duration and/or greater intensity can slow RPR in older persons.

Indexed as

AgedAged, 80 and overAge FactorsCardiovascular DiseasesExercise TherapyFemaleHeart RateHumansIncidenceMaleMotor ActivityPrognosisRestSingle-Blind MethodUnited States

Identifiers

PMID25262271
PMCPMC4180058
OpenAlexW2076824760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.