ArticleJournal of the mechanical behavior of biomedical materials2014
Incorporating plasticity of the interfibrillar matrix in shear lag models is necessary to replicate the multiscale mechanics of tendon fascicles.
Article in Journal of the mechanical behavior of biomedical materials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Structural determinants of tendon multiscale mechanics and their sensitivity to mechanical stimulation during development in an embryonic chick model.Acta biomaterialia · 2024Article
- Mechanical Models of Collagen Networks for Understanding Changes in the Failure Properties of Aging Skin.Journal of biomechanical engineering · 2024Article
- Mouse Achilles tendons exhibit collagen disorganization but minimal collagen denaturation during cyclic loading to failure.Journal of biomechanics · 2023Article
- An indentation-based framework for probing the glycosaminoglycan-mediated interactions of collagen fibrils.Journal of the mechanical behavior of biomedical materials · 2023Article
- Mechanical StimulationFrontiers in cell and developmental biology · 2021Article
- Dependence of tendon multiscale mechanics on sample gauge length is consistent with discontinuous collagen fibrils.Acta biomaterialia · 2020Article
- Helical fibrillar microstructure of tendon using serial block-face scanning electron microscopy and a mechanical model for interfibrillar load transfer.Journal of the Royal Society, Interface · 2019Article
- Multi-Scale Loading and Damage Mechanisms of Plantaris and Rat Tail Tendons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Article
- Comparative multi-scale hierarchical structure of the tail, plantaris, and Achilles tendons in the rat.Journal of anatomy · 2019Article
- Evidence that interfibrillar load transfer in tendon is supported by small diameter fibrils and not extrafibrillar tissue components.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2017Article
- Investigating mechanisms of tendon damage by measuring multi-scale recovery following tensile loading.Acta biomaterialia · 2017Article
- Mechanical function near defects in an aligned nanofiber composite is preserved by inclusion of disorganized layers: Insight into meniscus structure and function.Acta biomaterialia · 2017Article
- Multiscale modeling methods in biomechanics.Wiley interdisciplinary reviews. Systems biology and medicine · 2017Review
- Collagenous Extracellular Matrix Biomaterials for Tissue Engineering: Lessons from the Common Sea Urchin Tissue.International journal of molecular sciences · 2017Review
- Tendon exhibits complex poroelastic behavior at the nanoscale as revealed by high-frequency AFM-based rheology.Journal of biomechanics · 2017Article
- Novel human intervertebral disc strain template to quantify regional three-dimensional strains in a population and compare to internal strains predicted by a finite element model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2016Article
- Modelling approaches for evaluating multiscale tendon mechanics.Interface focus · 2016Article
- Quantification of Interfibrillar Shear Stress in Aligned Soft Collagenous Tissues via Notch Tension Testing.Scientific reports · 2015Article
- Micromechanical poroelastic finite element and shear-lag models of tendon predict large strain dependent Poisson's ratios and fluid expulsion under tensile loading.Acta biomaterialia · 2015Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Despite current knowledge of tendon structure, the fundamental deformation mechanisms underlying tendon mechanics and failure are unknown. We recently showed that a shear lag model, which explicitly assumed plastic interfibrillar load transfer between discontinuous fibrils, could explain the multiscale fascicle mechanics, suggesting that fascicle yielding is due to plastic deformation of the interfibrillar matrix. However, it is unclear whether alternative physical mechanisms, such as elastic interfibrillar deformation or fibril yielding, also contribute to fascicle mechanical behavior. The objective of the current work was to determine if plasticity of the interfibrillar matrix is uniquely capable of explaining the multiscale mechanics of tendon fascicles including the tissue post-yield behavior. This was examined by comparing the predictions of a continuous fibril model and three separate shear lag models incorporating an elastic, plastic, or elastoplastic interfibrillar matrix with multiscale experimental data. The predicted effects of fibril yielding on each of these models were also considered. The results demonstrated that neither the continuous fibril model nor the elastic shear lag model can successfully predict the experimental data, even if fibril yielding is included. Only the plastic or elastoplastic shear lag models were capable of reproducing the multiscale tendon fascicle mechanics. Differences between these two models were small, although the elastoplastic model did improve the fit of the experimental data at low applied tissue strains. These findings suggest that while interfibrillar elasticity contributes to the initial stress response, plastic deformation of the interfibrillar matrix is responsible for tendon fascicle post-yield behavior. This information sheds light on the physical processes underlying tendon failure, which is essential to improve our understanding of tissue pathology and guide the development of successful repair.
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