ArticleNature materials2014
Direct correlation of single-molecule properties with bulk mechanical performance for the biomimetic design of polymers.
Article in Nature materials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Force Reveals Hidden Conformations and Dissociation Pathways in Individual π-Interacting Dimers.Angewandte Chemie (International ed. in English) · 2026Article
- DNA-Intercalating Supramolecular Hydrogels for Tunable Thermal and Viscoelastic Properties.Angewandte Chemie (International ed. in English) · 2024Article
- Azobenzene as a photoswitchable mechanophore.Nature chemistry · 2024Article
- Self-Healing, Robust, Liquid-Repellent Coatings Exploiting the Donor-Acceptor Self-Assembly.ACS applied materials & interfaces · 2023Article
- The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterials.Frontiers in bioengineering and biotechnology · 2023Article
- Review
- Protein Hydrogels: The Swiss Army Knife for Enhanced Mechanical and Bioactive Properties of Biomaterials.Nanomaterials (Basel, Switzerland) · 2021Review
- Thermo-Viscoelastic Response of Protein-Based Hydrogels.Bioengineering (Basel, Switzerland) · 2021Article
- Self-Assembly and Genetically Engineered Hydrogels.Advances in biochemical engineering/biotechnology · 2021Review
- Towards photoswitchable quadruple hydrogen bondsChemical science · 2020Article
- A Polymer with Mechanochemically Active Hidden Length.Journal of the American Chemical Society · 2020Article
- Cytoskeleton-inspired artificial protein design to enhance polymer network elasticity.Macromolecules · 2020Article
- Complex polymer architectures through free-radical polymerization of multivinyl monomers.Nature reviews. Chemistry · 2020Review
- The molecular mechanisms underlying mussel adhesion.Nanoscale advances · 2019Review
- Dynamic force spectroscopy of synthetic oligorotaxane foldamers.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy.Molecules (Basel, Switzerland) · 2018Article
- Rationally designed synthetic protein hydrogels with predictable mechanical properties.Nature communications · 2018Article
- Multi-modal mechanophores based on cinnamate dimers.Nature communications · 2017Article
- Hydrogen bonding asymmetric star-shape derivative of bile acid leads to supramolecular fibrillar aggregates that wrap into micrometer spheres.Soft matter · 2016Article
- Advancing biomaterials of human origin for tissue engineering.Progress in polymer science · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For rational design of advanced polymeric materials, it is critical to establish a clear mechanistic link between the molecular structure of a polymer and the emergent bulk mechanical properties. Despite progress towards this goal, it remains a major challenge to directly correlate the bulk mechanical performance to the nanomechanical properties of individual constituent macromolecules. Here, we show a direct correlation between the single-molecule nanomechanical properties of a biomimetic modular polymer and the mechanical characteristics of the resulting bulk material. The multi-cyclic single-molecule force spectroscopy (SMFS) data enabled quantitative derivation of the asymmetric potential energy profile of individual module rupture and re-folding, in which a steep dissociative pathway accounted for the high plateau modulus, while a shallow associative well explained the energy-dissipative hysteresis and dynamic, adaptive recovery. These results demonstrate the potential for SMFS to serve as a guide for future rational design of advanced multifunctional materials.
Indexed as
Identifiers
25262095What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.