ReviewHearing research2015
Importance of cochlear health for implant function.
Review in Hearing research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06375278 (Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation), which is not on this map. Cited by 79 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation
Who cites it
79 citing papers in PubMed.
- Neural Hearing Loss: Mechanisms, Diagnosis and Treatment Horizons.Journal of the Association for Research in Otolaryngology : JARO · 2026Review
- Evaluation of Spiral Ganglion Lesions by Electrophysiological Measures.Brain sciences · 2026Article
- Establishing reliable neural health measures in adult cochlear implant users.Frontiers in neuroscience · 2026Article
- Threshold-distance functions predict speech recognition with cochlear implants.Scientific reports · 2025Article
- A comparison of electrophysiological measures for characterizing the cochlear-implant electrode-neuron interface.JASA express letters · 2025Article
- The State of High-Resolution Imaging of the Human Inner Ear: A Look Into the Black Box.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- An Electrically Evoked Compound Action Potential Marker for Local Spiral Ganglion Neuron Degeneration: The Failure Index.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Greenwood function shows close alignment with pitch perceived by cochlear implant patients with long, flexible electrode arrays and fine-structure stimulation.Frontiers in neuroscience · 2025Article
- Is there a difference in the spread of excitation at different electrode locations along the cochlea?CoDAS · 2025Article
- Is the spread of excitation different between adults and children cochlear implants users?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Artifact removal by template subtraction enables recordings of the frequency following response in cochlear-implant users.Scientific reports · 2024Article
- Dynamic micro-optical coherence tomography enables structural and metabolic imaging of the mammalian cochlea.Frontiers in molecular neuroscience · 2024Article
- Electrically evoked late latency response using single electrode stimulation and its relation to speech perception among paediatric cochlear implant users.Frontiers in human neuroscience · 2024Article
- Spectral Grouping of Electrically Encoded Sound Predicts Speech-in-Noise Performance in Cochlear Implantees.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Anatomical Variations of the Human Cochlea Using an Image Analysis Tool.Journal of clinical medicine · 2023Article
- Photobiomodulation Can Enhance Stem Cell Viability in Cochlea with Auditory Neuropathy but Does Not Restore Hearing.Stem cells international · 2023Article
- Changes in the Electrically Evoked Compound Action Potential over time After Implantation and Subsequent Deafening in Guinea Pigs.Journal of the Association for Research in Otolaryngology : JARO · 2022Article
- The intraoperative relationship between intracochlear electrical field and excitability of the auditory nerve.Heliyon · 2022Article
- Comparison of response properties of the electrically stimulated auditory nerve reported in human listeners and in animal models.Hearing research · 2022Review
- Assessing the Relationship Between Pitch Perception and Neural Health in Cochlear Implant Users.Journal of the Association for Research in Otolaryngology : JARO · 2022Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Amazing progress has been made in providing useful hearing to hearing-impaired individuals using cochlear implants, but challenges remain. One such challenge is understanding the effects of partial degeneration of the auditory nerve, the target of cochlear implant stimulation. Here we review studies from our human and animal laboratories aimed at characterizing the health of the implanted cochlea and the auditory nerve. We use the data on cochlear and neural health to guide rehabilitation strategies. The data also motivate the development of tissue-engineering procedures to preserve or build a healthy cochlea and improve performance obtained by cochlear implant recipients or eventually replace the need for a cochlear implant. This article is part of a Special Issue entitled <Lasker Award>.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.