ArticleMolecular systems biology2014
Plasma membrane H⁺ -ATPase regulation is required for auxin gradient formation preceding phototropic growth.
Article in Molecular systems biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 52 citations in OpenAlex.
- Phase-contrast microtomography unveils mechanisms of root colonization by a vascular fungal pathogen.Nature communications · 2026Article
- Cytosolic- and membrane-localized oxidized indole-3-acetic acid formation regulates developmental auxin transients.Plant physiology · 2025Article
- Regulation of tissue growth in plants - A mathematical modeling study on shade avoidance response inFrontiers in plant science · 2024Article
- Hydrogen peroxide mediates high-intensity blue light-induced hypocotyl phototropism of cotton seedlings.Stress biology · 2023Article
- Phototropin-mediated perception of light direction in leaves regulates blade flattening.Plant physiology · 2021Article
- Grape Small Auxin Upregulated RNA (International journal of molecular sciences · 2021Article
- A BLUS1 kinase signal and a decrease in intercellular CO2 concentration are necessary for stomatal opening in response to blue light.The Plant cell · 2021Article
- Deetiolation Enhances Phototropism by Modulating NON-PHOTOTROPIC HYPOCOTYL3 Phosphorylation Status.Plant physiology · 2019Article
- Evolutionary and Functional Analysis of aFrontiers in plant science · 2019Article
- Auxin methylation is required for differential growth inProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Functional Analysis of MAX2 in Phototropins-Mediated Cotyledon Flattening inFrontiers in plant science · 2018Article
- Mass Spectrometric Analyses Reveal a Central Role for Ubiquitylation in Remodeling the Arabidopsis Proteome during Photomorphogenesis.Molecular plant · 2017Article
- Cellulose Synthesis and Cell Expansion Are Regulated by Different Mechanisms in Growing Arabidopsis Hypocotyls.The Plant cell · 2017Article
- The Role of the Plasma Membrane HFrontiers in plant science · 2017Review
- Auxin enhances aluminium-induced citrate exudation through upregulation of GmMATE and activation of the plasma membrane H+-ATPase in soybean roots.Annals of botany · 2016Article
- Article
- Quantitative Proteomic Analysis of Wheat Seeds during Artificial Ageing and Priming Using the Isobaric Tandem Mass Tag Labeling.PloS one · 2016Article
- Phytochrome A Mediates Blue-Light Enhancement of Second-Positive Phototropism in Arabidopsis.Frontiers in plant science · 2016Article
- Regulation of the plasma membrane proton pump (H(+)-ATPase) by phosphorylation.Current opinion in plant biology · 2015Review
- SAUR Proteins as Effectors of Hormonal and Environmental Signals in Plant Growth.Molecular plant · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phototropism is a growth response allowing plants to align their photosynthetic organs toward incoming light and thereby to optimize photosynthetic activity. Formation of a lateral gradient of the phytohormone auxin is a key step to trigger asymmetric growth of the shoot leading to phototropic reorientation. To identify important regulators of auxin gradient formation, we developed an auxin flux model that enabled us to test in silico the impact of different morphological and biophysical parameters on gradient formation, including the contribution of the extracellular space (cell wall) or apoplast. Our model indicates that cell size, cell distributions, and apoplast thickness are all important factors affecting gradient formation. Among all tested variables, regulation of apoplastic pH was the most important to enable the formation of a lateral auxin gradient. To test this prediction, we interfered with the activity of plasma membrane H⁺ -ATPases that are required to control apoplastic pH. Our results show that H⁺ -ATPases are indeed important for the establishment of a lateral auxin gradient and phototropism. Moreover, we show that during phototropism, H⁺ -ATPase activity is regulated by the phototropin photoreceptors, providing a mechanism by which light influences apoplastic pH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.