Evidence map›Paper›PMID 25261349›Full record

ArticleBehavioral and brain functions : BBF2014

Reduced resting-state brain activity in the default mode network in children with (central) auditory processing disorders.

Agnieszka Pluta, Tomasz Wolak, Natalia Czajka, Monika Lewandowska, Katarzyna Cieśla, Mateusz Rusiniak, Diana Grudzień, Henryk Skarżyński

Registry-linked trialAbstract read
In one paragraph

Article in Behavioral and brain functions : BBF, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03887182 (Contribution of Functional MRI in Assessment of Auditory Processing Disorders), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03887182 nacompletednot on this mapstarted 2020, after this paper: background citation

Contribution of Functional MRI in Assessment of Auditory Processing Disorders

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2020 to 2023Enrolled45ConditionsAuditory Processing DisordersArmsfunctional MRI, Automated Cortical Brainstem Auditory Evoked Potential, whole exome sequencing, Standard Cortical Brainstem Auditory Evoked Potential, multidisciplinary consultation
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Dichotic listening deficits in amblyaudia are characterized by aberrant neural oscillations in auditory cortex.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Agnieszka PlutaWorld Hearing Center of the Institute of Physiology and Pathology of Hearing, Mokra 17 street, 05-830 Nadarzyn, Warsaw/Kajetany, Poland. a.pluta@ifps.org.pl.
Tomasz Wolak
Natalia Czajka
Monika Lewandowska
Katarzyna Cieśla
Mateusz Rusiniak
Diana Grudzień
Henryk Skarżyński

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, there has been a growing interest in Central Auditory Processing Disorder (C)APD. However, the neural correlates of (C)APD are poorly understood. Previous neuroimaging experiments have shown changes in the intrinsic activity of the brain in various cognitive deficits and brain disorders. The present study investigated the spontaneous brain activity in (C)APD subjects with resting-state fMRI (rs-fMRI).

methodsThirteen children diagnosed with (C)APD and fifteen age and gender-matched controls participated in a rs-fMRI study during which they were asked to relax keeping their eyes open. Two different techniques of the rs-fMRI data analysis were used: Regional Homogeneity (ReHo) and Independent Component Analysis (ICA), which approach is rare.

resultsBoth methods of data analysis showed comparable results in the pattern of DMN activity within groups. Additionally, ReHo analysis revealed increased co-activation of the superior frontal gyrus, the posterior cingulate cortex/the precuneus in controls, compared to the (C)APD group. ICA yielded inconsistent results across groups.

conclusionsOur ReHo results suggest that (C)APD children seem to present reduced regional homogeneity in brain regions considered a part of the default mode network (DMN). These findings might contribute to a better understanding of neural mechanisms of (C)APD.

Indexed as

AdolescentAuditory Perceptual DisordersBrainBrain MappingChildFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleNerve Net

Identifiers

PMID25261349
PMCPMC4236576

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.