ArticlePituitary2015
Endoscopic endonasal transsellar approach for laterally extended pituitary adenomas: volumetric analysis of cavernous sinus invasion.
Article in Pituitary, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Endoscopic endonasal transcavernous surgery for knosp grade 3-4 growth hormone-secreting pituitary neuroendocrine tumors: surgical outcomes and predictors of biochemical remission.Neurosurgical review · 2026Article
- Robotic-like maneuverability in endoscopic endonasal surgery: clinical experience with manually operated steerable forceps.Journal of robotic surgery · 2025Article
- Anatomical Step-by-Step Dissection of Complex Skull Base Approaches for Trainees: Surgical Anatomy of the Endoscopic Endonasal Approach to the Sellar and Parasellar Regions.Journal of neurological surgery. Part B, Skull base · 2023Article
- Advances in Pituitary Surgery.Endocrinology and metabolism (Seoul, Korea) · 2022Review
- Pituitary adenoma with posterior area invasion of cavernous sinus: surgical anatomy, approach, and outcomes.Neurosurgical review · 2021Article
- Results of Endoscopic Surgery in Patients with Pituitary Adenomas : Association of Tumor Classification Grades with Resection, Remission, and Complication Rates.Journal of Korean Neurosurgical Society · 2021Article
- Outcomes and Complications of Aggressive Resection Strategy for Pituitary Adenomas in Knosp Grade 4 With Transsphenoidal Endoscopy.Frontiers in oncology · 2021Article
- Preoperative prediction of cavernous sinus invasion by pituitary adenomas using a radiomics method based on magnetic resonance images.European radiology · 2019Article
- Surgical Treatment of Cavernous Sinus Lesion in Patients with Nonfunctioning Pituitary Adenomas via the Endoscopic Endonasal Approach.Journal of neurological surgery. Part B, Skull base · 2018Article
- Endoscopic transsellar approach to pituitary adenomas with cavernous sinus invasion: Is this just a matter of lateral extension?Pituitary · 2016Article
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Authors and funding
5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThe authors conducted a statistical analysis of surgical results of the endoscopic endonasal transsellar approach to provide quantitative indices for selection of the approach in the treatment of laterally extended pituitary adenomas.
methodsSurgical results of 25 patients with laterally extended pituitary adenomas of Knosp grade 3 or 4 were retrospectively analyzed. The removal rate was evaluated by the volumetric change of the lateral tumor compartment.
resultsThe transsellar approach was used exclusively in all cases. Gross total removal of the lateral tumor compartment was achieved in 14 (56.0%). Factors affecting the tumor removal through the transsellar approach were lateral tumor volume (p = 0.006), maximal distance to the cavernous sinus outer wall (p = 0.004) and history of previous surgery (p = 0.017). The cut-off values for the lateral tumor volume and maximal distance to the cavernous sinus outer wall predicting the gross total removal were 0.479 ml and 8.1 mm, respectively. The surgical complications of the transsellar approach included each case of anterior lobe function insufficiency and liquorrhea.
conclusionsThe transsellar approach is adequate for removal of lateral tumor compartment in the majority of cases with laterally extended pituitary adenomas. The tumor compartments dorsal and ventral to the horizontal portion of the intracavernous carotid artery are amenable to the removal. But for removal of the tumor compartment lateral to the carotid siphon requires additional use of the parasellar approach.
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