SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2015
Meniscal allograft transplantation. Part 1: systematic review of graft biology, graft shrinkage, graft extrusion, graft sizing, and graft fixation.
Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Comparison of Suture Versus Bony Fixation in Meniscal Allograft Transplantation Outcomes: A Meta-analysis.The American journal of sports medicine · 2025Pooled it
- The meniscotibial ligament role in meniscal extrusion: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2023Pooled it
- Meniscal allograft transplantation. Part 2: systematic review of transplant timing, outcomes, return to competition, associated procedures, and prevention of osteoarthritis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015Pooled it
- Capsular fixation limits graft extrusion in lateral meniscal allograft transplantation.International orthopaedics · 2019Trial
- Meniscal Root Fixation Method for Meniscus Transplantation: is There a Superior Technique?Current reviews in musculoskeletal medicine · 2026Review
- Integrated strategies in meniscus tissue engineering: from biomaterials to stem cell-driven regeneration.Frontiers in bioengineering and biotechnology · 2026Review
- Addressing meniscal deficiency part 1: An umbrella review of systematic reviews and meta-analyses on meniscal allograft transplantation.Journal of experimental orthopaedics · 2024Review
- Long-Term Clinical and Radiographic Outcomes of Meniscus Allograft Transplant.Current reviews in musculoskeletal medicine · 2024Review
- Article
- Could a three-dimensional contralateral meniscus segmentation for allograft or scaffold sizing be possible? A prospective study.International orthopaedics · 2023Article
- Meniscus Size Differs Between Patient and Donor Populations for Meniscus Allograft Transplantation.Arthroscopy, sports medicine, and rehabilitation · 2023Article
- Research landscape of 3D printing in bone regeneration and bone repair: A bibliometric and visualized analysis from 2012 to 2022.International journal of bioprinting · 2023Article
- Comparison of Radiologic Results after Lateral Meniscal Allograft Transplantation with or without Capsulodesis Using an All-Soft Suture Anchor.Medicina (Kaunas, Lithuania) · 2022Article
- Effect of Preoperative Joint Space Width on Lateral Meniscal Allograft Transplantation: Outcomes at Midterm Follow-up.Orthopaedic journal of sports medicine · 2022Article
- Human meniscus allograft augmentation by allogeneic mesenchymal stromal/stem cell injections.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
- [Arthroscopic meniscus transplantation without bone blocks].Operative Orthopadie und Traumatologie · 2021Review
- Epidemiology of Meniscal Allograft Transplantation at Children's Hospitals in the United States.Orthopaedic journal of sports medicine · 2021Article
- In Vivo Kinematic Analysis of Lateral Meniscal Allograft Transplantation With Soft Tissue Fixation.Orthopaedic journal of sports medicine · 2021Article
- Meniscus transplantation-prospective assessment of clinical results in two, five and ten year follow-up.International orthopaedics · 2021Article
- Imaging of meniscal allograft transplantation: what the radiologist needs to know.Skeletal radiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo provide a systematic review of the literature regarding five topics in meniscal allograft transplantation: graft biology, shrinkage, extrusion, sizing, and fixation.
methodsA systematic literature search was conducted using the PubMed (MEDLINE), ScienceDirect, and EBSCO-CINAHL databases. Articles were classified only in one topic, but information contained could be reported into other topics. Information was classified according to type of study (animal, in vitro human, and in vivo human) and level of evidence (for in vivo human studies).
resultsSixty-two studies were finally included: 30 biology, 3 graft shrinkage, 11 graft extrusion, 17 graft size, and 6 graft fixation (some studies were categorized in more than one topic). These studies corresponded to 22 animal studies, 22 in vitro human studies, and 23 in vivo human studies (7 level II, 10 level III, and 6 level IV).
conclusionsThe principal conclusions were as follows: (a) Donor cells decrease after MAT and grafts are repopulated with host cells form synovium; (b) graft preservation alters collagen network (deep freezing) and causes cell apoptosis with loss of viable cells (cryopreservation); (c) graft shrinkage occurs mainly in lyophilized and gamma-irradiated grafts (less with cryopreservation); (d) graft extrusion is common but has no clinical/functional implications; (e) overall, MRI is not superior to plain radiograph for graft sizing; (f) graft width size matching is more important than length size matching; (g) height appears to be the most important factor influencing meniscal size; (h) bone fixation better restores contact mechanics than suture fixation, but there are no differences for pullout strength or functional results; and (i) suture fixation has more risk of graft extrusion compared to bone fixation. LEVEL OF EVIDENCE: Systematic review of level II-IV studies, Level IV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.