Evidence map›Paper›PMID 25261010›Full record

ArticleThe American journal of medicine2015

The changing epidemiology of myocardial infarction in Olmsted County, Minnesota, 1995-2012.

Yariv Gerber, Susan A Weston, Ruoxiang Jiang, Véronique L Roger

Abstract read
In one paragraph

Article in The American journal of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  19. Trends in Acute Myocardial Infarction by Race and Ethnicity.Journal of the American Heart Association · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yariv GerberDepartment of Health Sciences Research, Department of Medicine, Mayo Clinic, Rochester, Minn; Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel.
Susan A WestonDepartment of Health Sciences Research, Department of Medicine, Mayo Clinic, Rochester, Minn.
Ruoxiang JiangDepartment of Health Sciences Research, Department of Medicine, Mayo Clinic, Rochester, Minn.
Véronique L RogerDepartment of Health Sciences Research, Department of Medicine, Mayo Clinic, Rochester, Minn; Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, Minn. Electronic address: roger.veronique@mayo.edu.

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Heart Failure in the CommunityR01HL072435 · NHLBI · MAYO CLINIC ROCHESTER · PI ROGER, VERONIQUE LEE · 2003 to 2011
$6.0M
CORONARY DISEASE MORBIDITY AND MORTALITY IN A POPULATIONR01HL059205 · NHLBI · MAYO CLINIC ROCHESTER · PI ROGER, VERONIQUE LEE · 1998 to 2012
$4.6M
Ventricular remodeling and heart failure after myocardial infarction: a communityR01HL120957 · NHLBI · MAYO CLINIC ROCHESTER · PI ENRIQUEZ-SARANO, MAURICE, ROGER, VERONIQUE LEE · 2014 to 2017
$3.0M
NHLBI NIH HHS R01 HL059205NHLBI NIH HHS R01 HL072435NHLBI NIH HHS R01 HL120957NHLBI NIH HHS R01 HL59205NHLBI NIH HHS R01 HL72435NIA NIH HHS R01 AG034676
6 · The paper itself

Abstract

backgroundContemporary data on the epidemiology of myocardial infarction in the population are limited and derived primarily from cohorts of hospitalized myocardial infarction patients. We assessed temporal trends in incident and recurrent myocardial infarction, with further partitioning of the rates into prehospital deaths and hospitalized events, in a geographically defined community.

methodsAll myocardial infarction events recorded among Olmsted County, Minnesota residents aged 25 years and older from 1995-2012, including prehospital deaths, were classified into incident and recurrent. Standardized rates were calculated and temporal trends compared.

resultsAltogether, 5258 myocardial infarctions occurred, including 1448 (27.5%) recurrences; 430 (8.2%) prehospital deaths were recorded. Among hospitalized events, recurrent myocardial infarction was associated with greater mortality risk than incident myocardial infarction (age-, sex-, and year-adjusted hazard ratio, 1.49; 95% confidence interval, 1.37-1.61). Although the overall rate of myocardial infarction declined over time (average annual percent change, -3.3), the magnitude of the decline varied widely. Incident hospitalized myocardial infarction rate fell 2.7%/y, compared with decreases of 1.5%/y in recurrent hospitalized myocardial infarction, 14.1%/y in prehospital fatal incident myocardial infarction, and 12.3%/y in prehospital fatal recurrent myocardial infarction (all P for diverging trends < .05). These trends resulted in an increasing proportion of recurrences among hospitalized myocardial infarctions (25.3% in 1995-2000, 26.8% in 2001-2006, and 29.0% in 2007-2012, Ptrend = .02).

conclusionsOver the past 18 years, a heterogeneous decline in myocardial infarction rates occurred in Olmsted County, resulting in transitions from incident to recurrent events and from prehospital deaths to hospitalized myocardial infarctions. Recurrent myocardial infarction confers a worse prognosis, thereby stressing the need to optimize prevention strategies in the population.

Indexed as

AdultAgedAged, 80 and overEmergency Medical ServicesFemaleHospitalizationHumansIncidenceMaleMiddle AgedMinnesotaMyocardial InfarctionRecurrenceSurvival AnalysisEpidemiologyMyocardial infarctionPopulationPreventionTrends

Identifiers

PMID25261010
PMCPMC4306650

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.