Evidence map›Paper›PMID 25260796›Full record

ReviewNeuroscience bulletin2014

Brain dopaminergic system changes in drug addiction: a review of positron emission tomography findings.

Haifeng Hou, Chunyan Wang, Shaowei Jia, Shu Hu, Mei Tian

Open access · bronzeAbstract readReview
In one paragraph

Review in Neuroscience bulletin, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  7. New Repeat Polymorphism in theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
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  13. Review
  14. Neuro-molecular imaging.Neuroscience bulletin · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Haifeng HouDepartment of Nuclear Medicine, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Chunyan Wang
Shaowei Jia
Shu Hu
Mei Tian
Peking University Shenzhen Hospital · CN307th Hospital of Chinese People’s Liberation Army · CNSecond Affiliated Hospital of Zhejiang University · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine (DA) is considered crucial for the rewarding effects of drugs of abuse, but its role in addiction remains unclear. Positron emission tomography (PET) is the first technology used for in vivo measurement of components of the dopaminergic system in the human brain. In this article, we review the major findings from PET imaging studies on the involvement of DA in drug addiction, including presynaptic DA synthesis, vesicular monoamine transporter 2, the DA transporter, and postsynaptic DA receptors. These results have corroborated the role of DA in addiction and increased the understanding of its underlying mechanisms.

Indexed as

Positron-Emission TomographyAnimalsBrainDopamineDopamine Plasma Membrane Transport ProteinsFemaleHumansMaleSubstance-Related DisordersVesicular Monoamine Transport ProteinsDopamineDopamine Plasma Membrane Transport ProteinsVesicular Monoamine Transport Proteins

Identifiers

PMID25260796
PMCPMC5562592
OpenAlexW1989543402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.