ArticleHealth and quality of life outcomes2014
Chronic inflammation and quality of life in older adults: a cross-sectional study using biomarkers to predict emotional and relational outcomes.
Article in Health and quality of life outcomes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Effect of Ketogenic Diet on Quality of Life in Adults with Chronic Disease: A Systematic Review of Randomized Controlled Trials.Nutrients · 2021Pooled it
- Concurrent associations between objective markers and subjective markers of aging with indicators of successful aging: An integrative approach.European journal of ageing · 2026Article
- Endometriosis and Nutrition: Therapeutic Perspectives.Journal of clinical medicine · 2025Review
- Endometriosis and Adenomyosis: From Pathogenesis to Follow-Up.Current issues in molecular biology · 2025Review
- The Influence of Social Dynamics on Biological Aging and the Health of Historically Marginalized Populations: A Biopsychosocial Model for Health Disparities.International journal of environmental research and public health · 2024Review
- Quality of Life and C-Reactive Protein in Patients with Schizophrenia: A Cross-Sectional Study.Alpha psychiatry · 2024Article
- Impaired Well-Being and Insomnia as Residuals of Resolved Medical Conditions: Survey in the Italian Population.International journal of environmental research and public health · 2024Article
- Is there any association between type of dietary fat and quality of life in hemodialysis patients? A cross-sectional study.Frontiers in nutrition · 2024Article
- Vascular Inflammatory Markers as Predictors of Peripheral Arterial Disease Patients' Quality-of-Life Changes after Endovascular Treatment.Journal of clinical medicine · 2023Article
- The anemia-independent impact of myelodysplastic syndromes on health-related quality of life.Annals of hematology · 2021Article
- A comprehensive model of predictors of quality of life in older adults with schizophrenia: results from the CSA study.Social psychiatry and psychiatric epidemiology · 2021Article
- Long-term mortality and quality of life after trauma: an ancillary study from the prospective multicenter trial FROG-ICU.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021Article
- Associations between inflammatory markers and well-being during 12 weeks of basic military training.European journal of applied physiology · 2021Article
- Global Correlations Between Chronic Inflammation and Violent Incidents: Potential Behavioral Consequences of Inflammatory Illnesses Across Socio-Demographic Levels.International journal of general medicine · 2021Article
- Association Between Peripheral Blood Cell Count Abnormalities and Health-Related Quality of Life in the General Population.HemaSphere · 2021Article
- Serum inflammatory and oxidative stress biomarkers levels are associated with pain intensity, pressure pain threshold and quality of life in myofascial pain syndrome.BMC research notes · 2020Article
- Association between daily level of objective physical activity and C-Reactive protein in a representative national sample of adults with self-reported diagnosed arthritis or fibromyalgia.Rheumatology international · 2020Observational
- Relationships of blood proinflammatory markers with psychological resilience and quality of life in civilian women with posttraumatic stress disorder.Scientific reports · 2019Article
- Inflammation and quality of life in later life: findings from the health, well-being and aging study (SABE).Health and quality of life outcomes · 2019Article
- Health-related quality of life in adolescents and the retinal microvascular structure.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study explores relationships between chronic inflammation and quality of life, making a case for biopsychosocial modeling of these associations. It builds on research from social and clinical disciplines connecting chronic conditions, and inflammatory conditions specifically, to reduced quality of life.
methodsData from Wave I of the National Social Life, Health, and Aging Project are modeled using ordinal logistic and ordinary least-squares regression techniques. Inflammation is measured using C-reactive protein; quality of life is conceptualized as happiness with life overall as well as intimate relationships specifically.
resultsFor most NSHAP participants, chronic inflammation significantly predicts lower odds of reporting high QoL on both emotional and relational measures. Social structural factors do not confound these associations. Inconsistent results for participants with very high (over 6 mg/L) CRP measurements suggest additional social influences.
conclusionsFindings echo strong theoretical justification for investigating relationships between CRP and QoL in greater detail. Further research should explore possible mediation of these associations by sociomedical sequelae of chronic disease as well as social relationship dynamics. Elaboration is also needed on the mechanisms by which social disadvantage may cause chronic inflammation.
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Registered trials
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