ArticleThe journal of headache and pain2014
Sleep features and central sensitization symptoms in primary headache patients.
Article in The journal of headache and pain, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Sleep disturbances in tension-type headache: a systematic review and meta-analysis.Journal of neurology · 2026Pooled it
- Trial
- Saliva molecular inflammatory profiling in female migraine patients responsive to adjunctive cervical non-invasive vagus nerve stimulation: the MOXY Study.Journal of translational medicine · 2019Trial
- Integrating Nutrition and Physical Activity into the EXEMIG/01 Interdisciplinary Model for Chronic and High-Frequency Migraine.Nutrients · 2026Article
- Prevalence of Temporomandibular Disorders in Obstructive Sleep Apnea Patients and Relationship Between Temporomandibular Disorder Phenotypes and Severity of Sleep Apnea: An Observational Study.Journal of pharmacy & bioallied sciences · 2025Article
- Investigating the Association Between Central Sensitization and Breathing Pattern Disorders.Biomedicines · 2025Article
- Risk Factors and Consequences of Cutaneous Allodynia among Individuals with Migraine: A Scoping Review.Current pain and headache reports · 2025Article
- Central Sensitization-Related Symptoms and Influencing Factors on Health-Related Quality of Life among Frail Older Adults in Senior Day Care Centers: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- The Influence of Physical, Mental, and Cognitive Factors on Health-Related Quality of Life among Community-Dwelling Older Adults: A Focus on Central Sensitization-Related Symptoms.Geriatrics (Basel, Switzerland) · 2024Article
- Unraveling the directional relationship of sleep and migraine-like pain.Brain communications · 2024Article
- Clinical Correlates of Osmophobia in Primary Headaches: An Observational Study in Child Cohorts.Journal of clinical medicine · 2023Article
- Sleep Quality Mediates the Effect of Sensitization-Associated Symptoms, Anxiety, and Depression on Quality of Life in Individuals with Post-COVID-19 Pain.Brain sciences · 2022Article
- Poorer sleep quality in patients with chronic temporomandibular disorders compared to healthy controls.BMC musculoskeletal disorders · 2022Article
- Current Perspectives on the Impact of Chronic Migraine on Sleep Quality: A Literature Review.Nature and science of sleep · 2022Review
- Osmophobia in primary headache patients: associated symptoms and response to preventive treatments.The journal of headache and pain · 2021Observational
- Melatonin Moderates the Triangle of Chronic Pain, Sleep Architecture and Immunometabolic Traffic.Biomedicines · 2021Review
- Social Distancing in Chronic Migraine during the COVID-19 Outbreak: Results from a Multicenter Observational Study.Nutrients · 2021Observational
- Pathophysiological Bases of Comorbidity in Migraine.Frontiers in human neuroscience · 2021Review
- Effect of Sleep Quality on Headache-Related Impact in Primary Headache Disorders.Journal of clinical neurology (Seoul, Korea) · 2020Article
- Excess abdominal fat is associated with cutaneous allodynia in individuals with migraine: a prospective cohort study.The journal of headache and pain · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAssociation between sleep disorders and headache is largely known. The aim of the present study was to evaluate sleep quality and quantity in a large cohort of primary headache patients, in order to correlate these scores with symptoms of central sensitization as allodynia, pericranial tenderness and comorbidity with diffuse muscle-skeletal pain.
methodsOne thousand six hundreds and seventy primary headache out patients were submitted to the Medical Outcomes Study (MOS) within a clinical assessment, consisting of evaluation of frequency of headache, pericranial tenderness, allodynia and coexistence of fibromyalgia syndrome (FM).
resultsTen groups of primary headache patients were individuated, including patients with episodic and chronic migraine and tension type headache, mixed forms, cluster headache and other trigeminal autonomic cephalalgias. Duration but not sleep disturbances score was correlated with symptoms of central sensitization as allodynia and pericranial tenderness in primary headache patients. The association among allodynia, pericranial tenderness and short sleep characterized chronic migraine more than any other primary headache form. Patients presenting with FM comorbidity suffered from sleep disturbances in addition to reduction of sleep duration.
conclusionSelf reported duration of sleep seems a useful index to be correlated with allodynia, pericranial tenderness and chronic headache as a therapeutic target to be assessed in forthcoming studies aiming to prevent central sensitization symptoms development.
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