ArticlePloS one2014
Thermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 96 citations in OpenAlex.
- Conserved HSP60 structure with lineage- and context-specific regulation in cnidarians.Life science alliance · 2026Article
- Contact- and Water-Mediated Interactions With an Allelopathic Macroalga Drive Distinct Coral Microbiome and Metabolome.Environmental microbiology · 2025Article
- Structural and Evolutionary Relationships of Melanin Cascade Proteins in Cnidarian Innate Immunity.Integrative and comparative biology · 2024Article
- Prior heat stress increases pathogen susceptibility in the model cnidarian Exaiptasia diaphana.Communications biology · 2024Article
- Microbial and transcriptional response of Acropora valida and Turbinaria peltata to Vibrio coralliilyticus challenge: insights into corals disease resistance.BMC microbiology · 2024Article
- Mitigation ofApplied and environmental microbiology · 2024Article
- Global warming-related response after bacterial challenge in Astroides calycularis, a Mediterranean thermophilic coral.Scientific reports · 2024Article
- Multiomics data integration, limitations, and prospects to reveal the metabolic activity of the coral holobiont.FEMS microbiology ecology · 2024Review
- Evolutionary radiation and microbial community dynamics shape the thermal tolerance of Fungiidae in the southern South China Sea.Microbiology spectrum · 2024Article
- Expression plasticity regulates intraspecific variation in the acclimatization potential of a reef-building coral.Nature communications · 2022Article
- The seasonal behaviour of COVID-19 and its galectin-like culprit of the viral spike.Methods in microbiology · 2022Article
- The history, biological relevance, and potential applications for polyp bailout in corals.Ecology and evolution · 2021Review
- The Pacific Oyster Mortality Syndrome, a Polymicrobial and Multifactorial Disease: State of Knowledge and Future Directions.Frontiers in immunology · 2021Review
- Functional Characterization of Hexacorallia Phagocytic Cells.Frontiers in immunology · 2021Article
- The tropical coralWellcome open research · 2021Article
- Transcriptome Analyses of Immune System Behaviors in Primary Polyp of Coral Acropora digitifera Exposed to the Bacterial Pathogen Vibrio coralliilyticus under Thermal Loading.Marine biotechnology (New York, N.Y.) · 2020Article
- Gene expression kinetics of Exaiptasia pallida innate immune response to Vibrio parahaemolyticus infection.BMC genomics · 2020Article
- Contrasting Immunomodulatory Effects of Probiotic and Pathogenic Bacteria on Eastern Oyster,Vaccines · 2020Article
- Review
- Comparative genomic analysis of Vibrios yields insights into genes associated with virulence towards C. gigas larvae.BMC genomics · 2020Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Global change and its associated temperature increase has directly or indirectly changed the distributions of hosts and pathogens, and has affected host immunity, pathogen virulence and growth rates. This has resulted in increased disease in natural plant and animal populations worldwide, including scleractinian corals. While the effects of temperature increase on immunity and pathogen virulence have been clearly identified, their interaction, synergy and relative weight during pathogenesis remain poorly documented. We investigated these phenomena in the interaction between the coral Pocillopora damicornis and the bacterium Vibrio coralliilyticus, for which the infection process is temperature-dependent. We developed an experimental model that enabled unraveling the effects of thermal stress, and virulence vs. non-virulence of the bacterium. The physiological impacts of various treatments were quantified at the transcriptome level using a combination of RNA sequencing and targeted approaches. The results showed that thermal stress triggered a general weakening of the coral, making it more prone to infection, non-virulent bacterium induced an 'efficient' immune response, whereas virulent bacterium caused immuno-suppression in its host.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.