ArticleInternational journal of nanomedicine2014
Nanouric acid or nanocalcium phosphate as central nidus to induce calcium oxalate stone formation: a high-resolution transmission electron microscopy study on urinary nanocrystallites.
Article in International journal of nanomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Association between hyperuricemia and kidney stones in Southern China: a multicentre cross-sectional study.Frontiers in endocrinology · 2026Article
- In focus: perplexing increase of urinary stone disease in children, adolescent and young adult women and its economic impact.Frontiers in medicine · 2023Article
- Recent advances on the mechanisms of kidney stone formation (Review).International journal of molecular medicine · 2021Review
- Rare non-papillary lithiasis of calcium oxalate monohydrate generated on a central core of potassium urate.Urology case reports · 2021Article
- Size-dependent cellular uptake mechanism and cytotoxicity toward calcium oxalate on Vero cells.Scientific reports · 2017Article
- Inhibition of urinary macromolecule heparin on aggregation of nano-COM and nano-COD crystals.Molecules (Basel, Switzerland) · 2015Article
- Research progress on the relationship between nanocrystals and calcium oxalate stones.Science progressReview
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
purposeThis study aimed to accurately analyze the relationship between calcium oxalate (CaOx) stone formation and the components of urinary nanocrystallites.
methodHigh-resolution transmission electron microscopy (HRTEM), selected area electron diffraction, fast Fourier transformation of HRTEM, and energy dispersive X-ray spectroscopy were performed to analyze the components of these nanocrystallites.
resultsThe main components of CaOx stones are calcium oxalate monohydrate and a small amount of dehydrate, while those of urinary nanocrystallites are calcium oxalate monohydrate, uric acid, and calcium phosphate. The mechanism of formation of CaOx stones was discussed based on the components of urinary nanocrystallites.
conclusionThe formation of CaOx stones is closely related both to the properties of urinary nanocrystallites and to the urinary components. The combination of HRTEM, fast Fourier transformation, selected area electron diffraction, and energy dispersive X-ray spectroscopy could be accurately performed to analyze the components of single urinary nanocrystallites. This result provides evidence for nanouric acid and/or nanocalcium phosphate crystallites as the central nidus to induce CaOx stone formation.
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