Evidence map›Paper›PMID 25257573›Full record

ArticleAIDS research and human retroviruses2015

Progress towards an HIV cure: update from the 2014 International AIDS Society Symposium.

Jenny Louise Anderson, Rémi Fromentin, Giulio Maria Corbelli, Lars Østergaard, Anna Laura Ross

Open access · greenAbstract readConference Proceedings
In one paragraph

Article in AIDS research and human retroviruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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  12. Global strategies are required to cure and eliminate HBV infection.Nature reviews. Gastroenterology & hepatology · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Jenny Louise Anderson1 The Peter Doherty Institute, The University of Melbourne , Melbourne, Australia .
Rémi Fromentin
Giulio Maria Corbelli
Lars Østergaard
Anna Laura Ross
Aarhus University Hospital · DKInternational AIDS Society · CHVaccine & Gene Therapy Institute of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomedical research has led to profound advances in the treatment of HIV infection. Combination antiretroviral therapy (ART) now provides the means to readily control viral infection, and people living with HIV who receive timely and effective ART can expect to benefit from a life expectancy comparable to uninfected individuals. Nevertheless, despite effective treatment, ART does not fully restore the immune system and importantly HIV persists indefinitely in latent reservoirs, resulting in the need for life-long treatment. The challenges and limits of life-long treatment have spurred significant scientific interest and global investment into research towards an HIV cure. The International AIDS Society (IAS) 2014 Towards an HIV cure symposium brought together researchers and community to discuss the most recent advances in our understanding of latency and HIV reservoirs, and the clinical approaches towards an HIV cure under current investigation. This report summarizes and reviews some of the major findings discussed during the symposium.

Indexed as

Acquired Immunodeficiency SyndromeAIDS VaccinesAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBiomedical ResearchCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesEnzyme ActivationHumansNF-kappa BPositive Transcriptional Elongation Factor BTreatment OutcomeVirus LatencyAIDS VaccinesAnti-HIV AgentsNF-kappa BPositive Transcriptional Elongation Factor B

Identifiers

PMID25257573
PMCPMC4287112
OpenAlexW2104340446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.