Evidence map›Paper›PMID 25257534›Full record

ReviewInternational journal of molecular sciences2014

Chromatin structure and dynamics in hot environments: architectural proteins and DNA topoisomerases of thermophilic archaea.

Valeria Visone, Antonella Vettone, Mario Serpe, Anna Valenti, Giuseppe Perugino, Mosè Rossi, Maria Ciaramella

Open access · goldAbstract readComparative StudyReview
In one paragraph

Review in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. The Role of Archaeal Chromatin in Transcription.Journal of molecular biology · 2019
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Valeria VisoneInstitute of Biosciences and Bioresources, National Research Council of Italy, Naples 80131, Italy. valeria.visone@ibbr.cnr.it.
Antonella VettoneInstitute of Biosciences and Bioresources, National Research Council of Italy, Naples 80131, Italy. anna.valenti@ibbr.cnr.it.
Mario SerpeInstitute of Biosciences and Bioresources, National Research Council of Italy, Naples 80131, Italy. mario.serpe@ibbr.cnr.it.
Anna ValentiInstitute of Biosciences and Bioresources, National Research Council of Italy, Naples 80131, Italy. anna.valenti@ibbr.cnr.it.
Giuseppe PeruginoInstitute of Biosciences and Bioresources, National Research Council of Italy, Naples 80131, Italy. giuseppe.perugino@ibbr.cnr.it.
Mosè RossiInstitute of Biosciences and Bioresources, National Research Council of Italy, Naples 80131, Italy. mose.rossi@ibbr.cnr.it.
Maria CiaramellaInstitute of Biosciences and Bioresources, National Research Council of Italy, Naples 80131, Italy. maria.ciaramella@ibbr.cnr.it.
National Research Council · ITInstitute of Biosciences and Bioresources · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In all organisms of the three living domains (Bacteria, Archaea, Eucarya) chromosome-associated proteins play a key role in genome functional organization. They not only compact and shape the genome structure, but also regulate its dynamics, which is essential to allow complex genome functions. Elucidation of chromatin composition and regulation is a critical issue in biology, because of the intimate connection of chromatin with all the essential information processes (transcription, replication, recombination, and repair). Chromatin proteins include architectural proteins and DNA topoisomerases, which regulate genome structure and remodelling at two hierarchical levels. This review is focussed on architectural proteins and topoisomerases from hyperthermophilic Archaea. In these organisms, which live at high environmental temperature (>80 °C <113 °C), chromatin proteins and modulation of the DNA secondary structure are concerned with the problem of DNA stabilization against heat denaturation while maintaining its metabolic activity.

Indexed as

Hot TemperatureArchaeaArchaeal ProteinsChromatinClimateDNA, ArchaealDNA-Binding ProteinsDNA TopoisomerasesDNA Topoisomerases, Type IGene Expression Regulation, ArchaealGenes, ArchaealHistonesNucleic Acid ConformationNucleosomesProtein BindingProtein ConformationArchaeal ProteinsChromatinDNA, ArchaealDNA-Binding ProteinsDNA reverse gyraseDNA TopoisomerasesDNA Topoisomerases, Type IHistonesNucleosomes

Identifiers

PMID25257534
PMCPMC4200833
OpenAlexW2027535017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.