Evidence map›Paper›PMID 25257188›Full record

ArticleJournal of the American Society for Mass Spectrometry2014

Simulation of electric potentials and ion motion in planar electrode structures for lossless ion manipulations (SLIM).

Sandilya V B Garimella, Yehia M Ibrahim, Ian K Webb, Aleksey V Tolmachev, Xinyu Zhang, Spencer A Prost, Gordon A Anderson, Richard D Smith

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. SLIM Tricks: Tools, Concepts, and Strategies for the Development of Planar Ion Guides.Journal of the American Society for Mass Spectrometry · 2023
    Article
  5. Enhancing the Depth of Analyses with Next-Generation Ion Mobility Experiments.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023
    Review
  6. A Flexible, Modular Platform for Multidimensional Ion Mobility of Native-like Ions.Journal of the American Society for Mass Spectrometry · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Dual Polarity Ion Confinement and Mobility Separations.Journal of the American Society for Mass Spectrometry · 2019
    Article
  17. Article
  18. Design of a TW-SLIM Module for Dual Polarity Confinement, Transport, and Reactions.Journal of the American Society for Mass Spectrometry · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sandilya V B GarimellaBiological Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA, 99352, USA.
Yehia M Ibrahim
Ian K Webb
Aleksey V Tolmachev
Xinyu Zhang
Spencer A Prost
Gordon A Anderson
Richard D Smith

Funding

Equipment Supplement Request for a Research Resource for Ultra-sensitive High Throughput ProteomicsP41GM103493 · NIGMS · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI SMITH, RICHARD D · 2012 to 2022
$22.6M
Multidimensional proteomics platformR21GM103497 · NIGMS · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI IBRAHIM, YEHIA · 2012 to 2012
$201k
NIGMS NIH HHS P41 GM103493NIGMS NIH HHS P41GM103493NIGMS NIH HHS R21 GM103497
6 · The paper itself

Abstract

We report a conceptual study and computational evaluation of novel planar electrode structures for lossless ion manipulations (SLIM). Planar electrode SLIM components were designed that allow for flexible ion confinement, transport, and storage using a combination of radio frequency (rf) and DC fields. Effective potentials can be generated that provide near ideal regions for confining and manipulating ions in the presence of a gas. Ion trajectory simulations using SIMION 8.1 demonstrated the capability for lossless ion motion in these devices over a wide m/z range and a range of electric fields at low pressures (e.g., a few Torr). More complex ion manipulations (e.g., turning ions by 90(o) and dynamically switching selected ion species into orthogonal channels) are also shown feasible. The performance of SLIM devices at ~4 Torr pressure for performing ion mobility-based separations (IMS) is computationally evaluated and compared with initial experimental results, and both are also shown to agree closely with experimental and theoretical IMS performance for a conventional drift tube design.

Indexed as

Computer SimulationElectrodesElectromagnetic FieldsEquipment DesignIonsMass SpectrometryIons

Identifiers

PMID25257188
PMCPMC4198429

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.