Evidence map›Paper›PMID 25257067›Full record

ArticleThe British journal of psychiatry : the journal of mental science2014

Fetal growth and psychiatric and socioeconomic problems: population-based sibling comparison.

Quetzal A Class, Martin E Rickert, Henrik Larsson, Paul Lichtenstein, Brian M D'Onofrio

Abstract read
In one paragraph

Article in The British journal of psychiatry : the journal of mental science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Parental asthma and risk of autism spectrum disorder in offspring: A population and family-based case-control study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Quetzal A ClassQuetzal A. Class, BS, Martin E. Rickert, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana; Henrik Larsson, PhD, Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Brian M. D'Onofrio, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana.
Martin E RickertQuetzal A. Class, BS, Martin E. Rickert, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana; Henrik Larsson, PhD, Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Brian M. D'Onofrio, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana.
Henrik LarssonQuetzal A. Class, BS, Martin E. Rickert, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana; Henrik Larsson, PhD, Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Brian M. D'Onofrio, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana.
Paul LichtensteinQuetzal A. Class, BS, Martin E. Rickert, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana; Henrik Larsson, PhD, Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Brian M. D'Onofrio, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana.
Brian M D'OnofrioQuetzal A. Class, BS, Martin E. Rickert, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana; Henrik Larsson, PhD, Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Brian M. D'Onofrio, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana.

Funding

Quasi-experimental studies of early risk factors for severe psychopathologyR01HD061817 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI D'ONOFRIO, BRIAN M, LICHTENSTEIN, PAUL · 2010 to 2013
$1.3M
Early Stress and Suicidal BehaviorF31MH094011 · NIMH · TRUSTEES OF INDIANA UNIVERSITY · PI CLASS, QUETZAL ATHENA · 2011 to 2012
$83k
NICHD NIH HHS HD061817NICHD NIH HHS R01 HD061817NIMH NIH HHS F31 MH094011NIMH NIH HHS MH094011
6 · The paper itself

Abstract

backgroundIt is unclear whether associations between fetal growth and psychiatric and socioeconomic problems are consistent with causal mechanisms.

aimsTo estimate the extent to which associations are a result of unmeasured confounding factors using a sibling-comparison approach.

methodWe predicted outcomes from continuously measured birth weight in a Swedish population cohort (n = 3 291 773), while controlling for measured and unmeasured confounding.

resultsIn the population, lower birth weight (⩽ 2500 g) increased the risk of all outcomes. Sibling-comparison models indicated that lower birth weight independently predicted increased risk for autism spectrum disorder (hazard ratio for low birth weight = 2.44, 95% CI 1.99-2.97) and attention-deficit hyperactivity disorder. Although attenuated, associations remained for psychotic or bipolar disorder and educational problems. Associations with suicide attempt, substance use problems and social welfare receipt, however, were fully attenuated in sibling comparisons.

conclusionsResults suggest that fetal growth, and factors that influence it, contribute to psychiatric and socioeconomic problems.

Indexed as

Birth WeightFetal DevelopmentSiblingsAdultChildFemaleHumansIncidenceMaleMental DisordersRisk FactorsSocioeconomic FactorsSuicide, Attempted

Identifiers

PMID25257067
PMCPMC4217026

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.