SynthesisJournal of cellular and molecular medicine2014
Evaluation of association of maternal IL-10 polymorphisms with risk of preeclampsia by A meta-analysis.
Synthesis in Journal of cellular and molecular medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Association Between Gene Polymorphisms on Chromosome 1 and Susceptibility to Pre-Eclampsia: An Updated Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2016Pooled it
- Association between Maternal and Fetal Genetic Variants and Preeclampsia: Evidence from a Meta-Analysis.Current issues in molecular biology · 2024Article
- Pre-Existing Diabetes Mellitus, Hypertension and KidneyDisease as Risk Factors of Pre-Eclampsia: A Disease of Theories and Its Association with Genetic Polymorphism.International journal of environmental research and public health · 2022Review
- Association of Matrix Metalloproteinase-9 Gene -1562C/T Polymorphism with Essential Hypertension: A Systematic Review and Meta-Analysis Article.Iranian journal of public health · 2015Review
- Evaluation of the relationship between T663A polymorphism in the alpha-epithelial sodium channel gene and essential hypertension.Saudi medical journal · 2015Review
- Association between Interleukin-10 gene polymorphisms and risk of early-onset preeclampsia.International journal of clinical and experimental pathology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging evidence shows that interleukin (IL)-10 gene polymorphisms can regulate its expression level and thus influence person's susceptibility to preeclampsia. However, various published results were inconsistent. To explore the association between maternal IL-10 gene polymorphisms and preeclampsia, we performed a meta-analysis based upon 11 individual studies here. Our meta-analysis results indicated that IL-10 -819 C/T (C versus T, OR = 1.28, 95% CI = 1.08-1.50, P = 0.003) and -592 C/A (C versus A, OR = 1.28, 95% CI = 1.03-1.59, P = 0.03) polymorphisms were associated with preeclampsia. Although there was no overall association between -1082 A/G polymorphism and preeclampsia (G versus A, OR = 0.93, 95% CI = 0.77-1.13, P = 0.49), such association existed among Asian (G versus A, OR = 1.29, 95% CI = 1.04-1.60, P = 0.02) and South American (G versus A, OR = 0.72, 95% CI = 0.54-0.94, P = 0.02) populations in the subgroup analysis stratified by continents.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.