Evidence map›Paper›PMID 25256939›Full record

SynthesisSurgery today2015

Pancreaticogastrostomy versus pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: a meta-analysis of randomized controlled trials.

Xianbin Zhang, Li Ma, Xiaohong Gao, Haidong Bao, Peng Liu, Ahsen- Aziz, Zhongyu Wang, Peng Gong

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Surgery today, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 5 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  5. Systematic review on the use of matrix-bound sealants in pancreatic resection.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015
    Pooled it
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  14. Polyester Preserves the Highest Breaking Point After Prolonged Incubation in Pancreatic Juice.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xianbin ZhangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Road, 116011, Dalian, Liaoning, China, bzmczxb@163.com.
Li Ma
Xiaohong Gao
Haidong Bao
Peng Liu
Ahsen- Aziz
Zhongyu Wang
Peng Gong
Dalian Medical University · CNFirst Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe conducted this meta-analysis to establish whether pancreaticogastrostomy (PG) or pancreaticojejunostomy (PJ) is the better method of reconstruction for reducing the risk of postoperative pancreatic fistula (POPF).

methodsThis study involved a systematic article search and review of published randomized controlled trials (RCTs) comparing PG vs. PJ after pancreaticoduodenectomy (PD). Cochrane's risk of bias-assessing tool was used to assess the quality of included studies. The fixed-effect model, random-effect model, and subgroup analysis were performed for the sensitivity analysis.

resultsSix RCTs reporting data on 998 patients were included. The incidence of POPF was lower in the PG group (risk ratio, RR = 0.65, 95 % CI 0.43-0.97, P = 0.03), but there was no significant difference in delayed gastric emptying, intra-abdominal fluid collection, biliary fistula, wound infection, postpancreatectomy hemorrhage, overall postoperative complication, or postoperative mortality between the procedures.

conclusionsThis meta-analysis shows that PG is superior to PJ for reducing the incidence of POPF, but there were no differences in other complications or mortality. Therefore, it may be considered as an alternative to PJ and further RCTs are needed to prove our findings.

Indexed as

GastrostomyPancreaticoduodenectomyPancreaticojejunostomyRandomized Controlled Trials as TopicAdultAgedAged, 80 and overDatabases, BibliographicFemaleHumansIncidenceMaleMiddle AgedPancreatic FistulaPostoperative ComplicationsRisk

Identifiers

PMID25256939
OpenAlexW2028206730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.