Evidence map›Paper›PMID 25256930›Full record

ReviewFertility and sterility2014

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: II. Clinical and covariate phenotype data collection in endometriosis research.

Allison F Vitonis, Katy Vincent, Nilufer Rahmioglu, Amelie Fassbender, Germaine M Buck Louis, Lone Hummelshoj, Linda C Giudice, Pamela Stratton, G David Adamson, Christian M Becker and 3 more

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Fertility and sterility, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 128 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05523284 enrolling by invitationnot on this mapstarted 2023, after this paper: background citation

Transvaginal Ultrasound-guided Culdocentesis for Peritoneal Fluid Cytokines in Patients With Possible Superficial Endometriosis But no Ultrasound-diagnosed Ovarian or Deep Endometriosis (SPG)

TypeobservationalSponsorMcMaster UniversityRan2023 to 2026Enrolled50ConditionsEndometriosis (Diagnosis), EndometriosisArmsSonoPODography
NCT06611501 phase2active not recruitingnot on this mapstarted 2025, after this paper: background citation

Glycemic Regulation as Endometriosis Adjunct Treatment

TypeinterventionalSponsorBoston Children's HospitalRan2025 to 2027Enrolled14ConditionsPelvic Pain, EndometriosisArmsMetformin Hydrochloride, Placebo
3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  5. Pooled it
  6. Pooled it
  7. Combination of the non-invasive tests for the diagnosis of endometriosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  8. Blood biomarkers for the non-invasive diagnosis of endometriosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  9. Endometrial biomarkers for the non-invasive diagnosis of endometriosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  10. Imaging modalities for the non-invasive diagnosis of endometriosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  11. Urinary biomarkers for the non-invasive diagnosis of endometriosis.The Cochrane database of systematic reviews · 2015
    Pooled it
  12. Trial
  13. Trial
  14. Trial
  15. Article
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  18. Review
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  20. Review

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Allison F VitonisDepartment of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Boston Center for Endometriosis, Boston Children's Hospital and Brigham and Women's Hospital, Boston, Massachusetts.
Katy VincentNuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom.
Nilufer RahmiogluWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Amelie FassbenderOrgan Systems, Department of Development and Regeneration, Katholieke Universiteit Leuven, Leuven, Belgium; Department of Obstetrics and Gynecology, Leuven University Fertility Center, University Hospital Leuven, Leuven, Belgium.
Germaine M Buck LouisDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
Lone HummelshojWorld Endometriosis Research Foundation (WERF), London, United Kingdom.
Linda C GiudiceWorld Endometriosis Research Foundation (WERF), London, United Kingdom; University of California-San Francisco, San Francisco, California.
Pamela StrattonProgram in Reproductive and Adult Endocrinology, Intramural Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
G David AdamsonWorld Endometriosis Research Foundation (WERF), London, United Kingdom; Palo Alto Medical Foundation Fertility Physicians of Northern California, Palo Alto, California.
Christian M BeckerNuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom; Endometriosis CaRe Centre Oxford, University of Oxford, Oxford, United Kingdom.
Krina T ZondervanNuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Endometriosis CaRe Centre Oxford, University of Oxford, Oxford, United Kingdom.
Stacey A MissmerDepartment of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Boston Center for Endometriosis, Boston Children's Hospital and Brigham and Women's Hospital, Boston, Massachusetts; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts. Electronic address: stacey.missmer@channing.harvard.edu.
WERF EPHect Working Group

Funding

Project 4: Human Endometrial Programming for Successful ImplantationP50HD055764 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GIUDICE, LINDA C · 2014 to 2022
$16.4M
Trophoblast Differentiation in In Vivo and In Vitro Fertilized EmbryosU54HD055764 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BLELLOCH, ROBERT · 2007 to 2013
$11.5M
Dioxin Exposure and the Invasive Pathogenesis of EndometriosisR01ES014942 · NIEHS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BRUNER-TRAN, KAYLON L, OSTEEN, KEVIN G · 2006 to 2016
$3.5M
Neural Immune and Genetic Influences on Chronic Pelvic Pain and EndometriosisZIAHD008769 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI STRATTON, PAMELA · 2009 to 2016
$2.1M
Immunology, Inflammation, and EndometriosisR01HD057210 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI MISSMER, STACEY ANN · 2009 to 2012
$1.4M
Chief Scientist OfficeIntramural NIH HHSMedical Research Council G0601458Medical Research Council MR/K011480/1NICHD NIH HHS HD57210NICHD NIH HHS P50 HD055764NICHD NIH HHS R01 HD057210NICHD NIH HHS U54 HD055764NICHD NIH HHS U54HD 055764NIEHS NIH HHS R01 ES014942Wellcome Trust 085235Wellcome Trust WT085235/Z/08/Z
6 · The paper itself

Abstract

objectiveTo harmonize the collection of nonsurgical clinical and epidemiologic data relevant to endometriosis research, allowing large-scale collaboration.

designAn international collaboration involving 34 clinical/academic centers and three industry collaborators from 16 countries on five continents.

settingIn 2013, two workshops followed by global consultation, bringing together 54 leaders in endometriosis research. PATIENTS: None. INTERVENTION(S): Development of a self-administered endometriosis patient questionnaire (EPQ), based on [1] systematic comparison of questionnaires from eight centers that collect data from endometriosis cases (and controls/comparison women) on a medium to large scale (publication on >100 cases); [2] literature evidence; and [3] several global consultation rounds. MAIN OUTCOME MEASURE(S): Standard recommended and minimum required questionnaires to capture detailed clinical and covariate data. RESULT(S): The standard recommended (EPHect EPQ-S) and minimum required (EPHect EPQ-M) questionnaires contain questions on pelvic pain, subfertility and menstrual/reproductive history, hormone/medication use, medical history, and personal information. CONCLUSION(S): The EPQ captures the basic set of patient characteristics and exposures considered by the WERF EPHect Working Group to be most critical for the advancement of endometriosis research, but is also relevant to other female conditions with similar risk factors and/or symptomatology. The instruments will be reviewed based on feedback from investigators, and-after a first review after 1 year-triannually through systematic follow-up surveys. Updated versions will be made available through http://endometriosisfoundation.org/ephect.

Indexed as

RegistriesSurveys and QuestionnairesBiomedical ResearchEducationEndometriosisFemaleHumansInformation Storage and RetrievalInternationalityMedical History TakingPhenotypeEndometriosisEPHect EPQpelvic painquestionnairestandardizationsymptoms

Identifiers

PMID25256930
PMCPMC4252538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.