ArticleStress (Amsterdam, Netherlands)2015
Smoking and perceived stress in relation to short salivary telomere length among caregivers of children with disabilities.
Article in Stress (Amsterdam, Netherlands), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Telomere length analysis from minimally-invasively collected samples: Methods development and meta-analysis of the validity of different sampling techniques: American Journal of Human Biology.American journal of human biology : the official journal of the Human Biology Council · 2021Pooled it
- Perceived stress and telomere length: A systematic review, meta-analysis, and methodologic considerations for advancing the field.Brain, behavior, and immunity · 2016Pooled it
- Caregiver burden and risk of epithelial ovarian cancer in the Nurses' Health Studies.American journal of epidemiology · 2025Article
- A standalone approach to utilize telomere length measurement as a surveillance tool in oral leukoplakia.Molecular oncology · 2022Article
- Testing Two Student Nurse Stress Instruments in Chinese Nursing Students: A Comparative Study Using Exploratory Factor Analysis.BioMed research international · 2020Article
- Social Relationships and Salivary Telomere Length Among Middle-Aged and Older African American and White Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2019Article
- Evaluating minimally invasive sample collection methods for telomere length measurement.American journal of human biology : the official journal of the Human Biology Council · 2018Article
- Marital disruption is associated with shorter salivary telomere length in a probability sample of older adults.Social science & medicine (1982) · 2016Article
- Review
- Associations of self-reported and objectively measured sleep disturbances with depression among primary caregivers of children with disabilities.Nature and science of sleep · 2016Article
- Article
- Social Determinants and Health Behaviors: Conceptual Frames and Empirical Advances.Current opinion in psychology · 2015Article
- Not all biofluids are created equal: chewing over salivary diagnostics and the epigenome.Clinical therapeutics · 2015Review
- Caregivers' hair cortisol: a possible biomarker of chronic stress is associated with obesity measures among children with disabilities.BMC pediatrics · 2015Article
- Telomere length is highly inherited and associated with hyperactivity-impulsivity in children with attention deficit/hyperactivity disorder.Frontiers in molecular neuroscience · 2015Article
- A Lens on Caregiver Stress in Cancer: Longitudinal Investigation of Cancer-Related Stress and Telomere Length Among Family Caregivers of Adult Patients With Cancer.Psychosomatic medicineArticle
- Depressive Symptoms and Salivary Telomere Length in a Probability Sample of Middle-Aged and Older Adults.Psychosomatic medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Telomere length (TL), the length of repeated DNA sequence that forms protective caps at the end of chromosomes, has emerged as a novel biomarker of cell aging and oxidative stress. There is increasing research exploring the associations of smoking and perceived stress with TL, and the results are inconsistent. This study aimed to examine whether smoking and perceived stress were associated with shortened salivary TL among primary caregivers of children with disabilities. Using a quantitative polymerase chain reaction method, salivary TL was assessed among 89 caregivers aged 19-69 years (87% were women) who took care of disabled children in the Patagonia Region, Chile. Interviewer-administered questionnaires were used to collect information on sociodemographic and lifestyle factors. The 14-item Perceived Stress Scale was used to assess perceived stress. Mean relative TL was 0.92 (standard error = 0.03). Smokers had age-adjusted mean TL that was 0.07 units lower (β = -0.07, standard error = 0.03; p = 0.012) than non-smokers. Smokers were 2.17 times more likely to have shorter TL ( < 0.73, the lowest quartile of TL) than non-smokers (odds ratio = 3.17; 95% confidence interval = 1.05-9.52) with adjustment for age and perceived stress. Caregivers with higher perceived stress were 2.13 times more likely to have shorter TL (odds ratio = 3.13; 95% confidence interval = 1.03-9.55) than caregivers with lower perceived stress after adjustment for age and smoking. This study provides the first evidence of strong associations between smoking and perceived stress and shortened salivary TL among caregivers of children with disabilities. Larger studies with detailed information on smoking status are warranted to confirm our findings.
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Registered trials
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