ReviewBiology2014
Preterm birth and its long-term effects: methylation to mechanisms.
Review in Biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 5 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Pooled it
- Impact of preterm birth on muscle mass and function: a systematic review and meta-analysis.European journal of pediatrics · 2024Pooled it
- Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.Genome medicine · 2020Pooled it
- A Systematic Review of DNA Methylation and Preterm Birth in African American Women.Biological research for nursing · 2017Pooled it
- Maternal exposure to di-2-ethylhexylphthalate and adverse delivery outcomes: A systematic review.Reproductive toxicology (Elmsford, N.Y.) · 2016Pooled it
- Intake of mother's milk by very-low-birth-weight infants and variation in DNA methylation of genes involved in neurodevelopment at 5.5 years of age.The American journal of clinical nutrition · 2022Trial
- Long-term health outcomes of preterm birth: a narrative review.Frontiers in pediatrics · 2025Review
- The influence of environmental factors related to Juvenile Dermatomyositis (JDM), its course and refractoriness to treatment.Advances in rheumatology (London, England) · 2024Article
- Epigenetic associations with neonatal age in infants born very preterm, particularly among genes involved in neurodevelopment.Scientific reports · 2024Article
- Antioxidant and neurodevelopmental gene polymorphisms in prematurely born individuals influence hypoxia-related oxidative stress.Scientific reports · 2024Article
- Interleukin-2 gene methylation levels and interleukin-2 levels associated with environmental exposure as risk biomarkers for preterm birth.Croatian medical journal · 2023Article
- Advances in Genetics and Epigenetics of Developmental Coordination Disorder in Children.Brain sciences · 2023Review
- Genetics, epigenetics, and transcriptomics of preterm birth.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022Review
- Diversified dietary intake and associated factors among pregnant mothers attending antenatal care follow-up in public health facilities of Dire Dawa, Eastern Ethiopia.PLOS global public health · 2022Article
- lncRNAInternational journal of molecular medicine · 2021Article
- Prenatal Exposure to Heavy Metals Affects Gestational Age by Altering DNA Methylation Patterns.Nanomaterials (Basel, Switzerland) · 2021Article
- Integrative analysis of transcriptomic data for identification of T-cell activation-related mRNA signatures indicative of preterm birth.Scientific reports · 2021Article
- Placental programming, perinatal inflammation, and neurodevelopment impairment among those born extremely preterm.Pediatric research · 2021Review
- Article
- Comparison of DNA methylation profiles associated with spontaneous preterm birth in placenta and cord blood.BMC medical genomics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The epigenetic patterns established during development may influence gene expression over a lifetime and increase susceptibility to chronic disease. Being born preterm (<37 weeks of gestation) is associated with increased risk mortality and morbidity from birth until adulthood. This brief review explores the potential role of DNA methylation in preterm birth (PTB) and its possible long-term consequences and provides an overview of the physiological processes central to PTB and recent DNA methylation studies of PTB.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.